Downloaded from http://journals.lww.com/acsm-msse by BhDMf5ePHKbH4TTImqenVLeEdd5NVDXpfXgAL78IUU/s18PTI0EuYL9MRLNxPmNGulq5Xc+06YA= on 03/09/2020 280 1052 Board #286 May 29 2:00 PM - 3:30 PM Effects Of Nsaid Use On Biomarkers Of Kidney Stress Following A Marathon Whitley C. Atkins 1 , Aaron R. Caldwell 1 , Cory L. Butts 2 , Lisa Jansen 1 , Melani R. Kelly 3 , Margaret Gibson 4 , Dawn M. Emerson 3 , Brendon P. McDermott, FACSM 1 . 1 University of Arkansas, Fayetteville, AR. 2 Weber State University, Ogden, UT. 3 University of Kansas, Lawrence, KS. 4 Truman Medical Center, Kansas City, MO. (No relationships reported) The use of nonsteroidal anti-inflammatory drugs (NSAID) is common practice by participants in marathons and other endurance events. Previous research suggests that renal stress is apparent immediately following marathon completion. However, the potential exacerbating effect of NSAID use during a marathon is not well-understood. PURPOSE: Investigate the effect of NSAID use on biomarkers of renal stress following a marathon. METHODS: Twenty-two volunteer participants (14 males, 8 females; 38 ± 10.2y, 70.7 ± 10.1kg, 171.0 ± 7.7cm) at the Kansas City Marathon were recruited and assigned to either a control (n = 15) or NSAID (n = 7) group based on planned or habitual use. Pre-race NSAID ingestion was self-reported as 9.15 ± 4.62 mg/kg of ibuprofen (n=4) or 3.75 ± 1.73mg/kg naproxen sodium (n=3). Urine samples were collected pre-marathon, post-marathon, and 24-h post-marathon. Samples were stored at -80°C and later analyzed for urinary neutrophil gelatinase lipocalin (uNGAL) and urinary cystatin C (uCyC). A robust two-way mixed ANOVA with trimmed means was utilized to account for potential outliers. When significant interaction or main effects were observed, pairwise comparisons were calculated using robust bootstrapped effect sizes with 95% confidence intervals. RESULTS: Immediately post-marathon, there was a significant increase in uNGAL (Cohen’s d R = 0.47 95%C.I. [0.23,0.85]) but there was no longer a significant elevation by 24-h post- marathon (Cohen's d R = 0.16 95%C.I. [-0.61,3.36]). There were no significant effects detected for Cystatin C. Further, NSAID ingestion did not affect uCyC or uNGAL values. CONCLUSION: Renal stress biomarkers suggest potential kidney tubular injury immediately post-marathon, but potential renal stress was negated by 24-h of recovery. Moderate NSAID ingestion before the marathon did not affect kidney stress biomarkers. 1053 Board #287 May 29 2:00 PM - 3:30 PM A Novel Assessment of Law Enforcement Officer Response to aDynamic Shooting Protocol JohnEric W. Smith 1 , Brandon D. Shepherd 1 , Teena M. Garrison 1 , Benjamin M. Krings 2 , Matthew J. McAllister 3 . 1 Mississippi State University, Mississippi State, MS. 2 University of Wisconsin-Platteville, Platteville, WI. 3 Texas State University, San Marcos, TX. Email: johneric.smith@msstate.edu (No relationships reported) Police officers’ responses to violent situations are frequently scrutinized. PURPOSE: This study was created to establish a Target Assessment, Action, and Accuracy Protocol (TAAAP), assessing law enforcement personnel’s decision making and firearm proficiency in a dynamic environment. We hypothesized the TAAAP would result in a greater performance differentiation than a traditional shooting test. METHODS: Healthy, non-colorblind, law enforcement officers (n=7) participated in four trials; traditional fatigued, TAAAP fatigued, traditional fresh, and TAAAP fresh. The traditional protocol required officers to fire eight shots in 15 s at a target 3 m away, then fire four rounds in 6 s at a target 6.1 m away. Following a magazine change, the protocol was repeated. The TAAAP consisted of multiple targets, both hostile and friendly, at varying distances across five separate shooting bays. Fatigued protocols required participants to run until volitional fatigue and shoot, whereas subjects had no physical exertion prior to beginning the fresh trials. Shooting accuracy and response time were collected and analyzed. RESULTS: The traditional shooting test demonstrated an accuracy rate of 88 +9% while the TAAAP demonstrated an accuracy rate of 49 +17%. The findings of the current study demonstrated TAAAP is a more challenging assessment tool as compared to traditional shooting tasks. CONCLUSIONS: While the traditional task demonstrated a potential ceiling effect, the TAAAP may provide a better example of shooting accuracy in naturalistic settings when compared to the results from officer involved shootings at less than 6.1 m. 1054 Board #288 May 29 2:00 PM - 3:30 PM Correlation Between V̇O2max and Anaerobic Power in Law Enforcement SWAT Team Members Shea B. Caddel, Matthew C. Jackson, Nicole C. Dabbs, Jason Ng. California State University, San Bernardino, San Bernardino, CA. (No relationships reported) PURPOSE: The purpose of this investigation was to examine the relationship between maximal oxygen uptake (V̇O 2max ) and anaerobic power in Special Weapons and Tactics (SWAT) team members of law enforcement. METHODS: Fourteen healthy men and one healthy woman (age: 33 ± 6 y, height: 179.6 ± 6.7 cm, body mass: 89.6 ± 10.4 kg) performed a graded exercise test to measure V̇O 2max and a Wingate Anaerobic Test to measure anaerobic power on two separate occasions. V̇O 2max was determined with a graded exercise test on a motorized treadmill using the Costill-Fox protocol. Anaerobic power was determined using the Wingate Anaerobic Test where participants cycled against a resistance of 9% of body mass (8 ± 1 kg) on a Wingate cycle ergometer. Pearson’s r correlations were conducted to analyze the relationship between absolute V̇O 2max and absolute power as well as relative V̇O 2max and relative power. RESULTS: Absolute V̇O 2max was significantly positively correlated to absolute peak power (r = 0.60; p = 0.02) and absolute average power (r = 0.75; p < 0.01). Moreover, relative V̇O 2max was significantly positively correlated to relative peak power (r = 0.56; p = 0.03) and relative average power (r = 0.64; p = 0.01). CONCLUSIONS: There are moderate-to-strong positive correlations between V̇O 2max and anaerobic power. It is possible that adaptations that occur with high intensity anaerobic exertions might be related to changes in aerobic metabolism. Future research might consider examining the effectiveness of anaerobic power training on aerobic fitness among the tactical athlete populations. 1055 Board #289 May 29 2:00 PM - 3:30 PM Influence Of Working Hours On Pregnancy Outcomes: A Systematic Review And Meta-analysis Margie H. Davenport, Robin Featherstone, Ben Vandermeer, Meghan Sebastianski, Chenxi Cai. University of Alberta, Edmonton, AB, Canada. Email: mdavenpo@ualberta.ca (No relationships reported) Approximately 90% of women remain employed during pregnancy. Long working hours have been hypothesized to be associated with an increased risk of adverse pregnancy outcomes including miscarriage and preterm delivery. PURPOSE: The purpose of this review was to evaluate the effect of long working hours (>40 hour work week) on maternal and fetal health outcomes. METHODS: Five electronic databases and two grey literature sources were searched up to March 12, 2018 and the results underwent duplicate independent screening. Studies of all designs were included (except case studies), and contained information on the Population [women who engaged in paid work during pregnancy], Exposure [>40 h work week], Comparator [working <=40 h/week], and Outcomes [preterm birth, low birthweight (birthweight<2,500g), small for gestational age, miscarriage, gestational hypertension, pre-eclampsia and intrauterine growth restriction]. Pooled odds ratio (OR) and 95% confidence interval (CI) were calculated using a random-effect, inverse variance method. Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework was used to assess the quality of evidence. RESULTS: A total of 41 observational studies (N=126,632) were included. “Low” to “Very low” quality evidence from observational studies revealed that compared with normal working hours (working <=40 h/week), long working hours were associated with an increased odds of having a preterm delivery (OR: 1.16, 95% CI: 1.04, 1.3, I 2 =53%), a small-for-gestational age baby Copyright © 2019 by the American College of Sports Medicine. Unauthorized reproduction of this article is prohibited.