* Corresponding author: Tarak Das Copyright © 2024 Author(s) retain the copyright of this article. This article is published under the terms of the Creative Commons Attribution Liscense 4.0. A simplified model for predicting ventricular hypertrophy than traditional methods Aditya Santra, Shuvangi Shaw and Tarak Das * Department of Biomedical Engineering, Netaji Subhash Engineering College, Kolkata, India. International Journal of Science and Research Archive, 2024, 12(01), 2636–2642 Publication history: Received on 08 May 2024; revised on 16 June 2024; accepted on 19 June 2024 Article DOI: https://doi.org/10.30574/ijsra.2024.12.1.1112 Abstract Ventricular hypertrophy is the thickening of the muscles in the ventricular chambers of the heart which stiffens and thickens the cardiac walls giving rise to many complications like arrhythmia, high blood pressure, or even heart failure. One of the ways to diagnose ventricular hypertrophy is through an Echocardiogram which can be predicted by the positive large amplitude of Chest Leads [V4–V6] of an Electrocardiogram (ECG). But chest lead application is one of the complicated more parts of the ECG than limb lead. Here we have tried to predict ventricular hypertrophy with bipolar limb lead electrocardiogram [L-I, L-II & L-III] without any chest leads which can be easily designed to make an ECG prototype instead of any sophisticated instruments to increase its global accessibility even in remote areas for the prediction of ventricular hypertrophy even may be for other diagnosis in future. We acquired electrocardiogram data sets from the physio-net database, specifically collected data from both normal and hypertrophic patients in an institute. These data sets were obtained using the same recording device. The Lead-I of the RVH and normal patients were not satisfactorily distinguishable. However, in this work, it has been established that Lead-I can be used to predict for identification of LVH patients. Keywords: Hypertrophy; LVH; ECG; Physio-net; RVH; MATLAB 1. Introduction In remote areas where the availability of high-end instruments and doctors are not available, it becomes hard for people to be diagnosed with cardiac ailments like hypertrophy in their initial stages. Ventricular Hypertrophy is a heart condition where the muscles in the ventricular heart chamber thicken and stiffen the blood circulation resulting in improper pumping of the heart. Ventricular hypertrophy is usually caused due to many reasons namely: gene mutations, overload of pressure induced by arteriolar vasoconstriction, aortic stenosis, obstructive cardiomyopathy, or even chronic hypertension. Ventricular hypertrophy can lead to conditions like arrhythmia, ischemia, and heart failure. One of the usual ways to predict ventricular hypertrophy from an ECG signal is to use the QRS complex amplitude of V4 to V6 lead. The volume overload in the ventricles is depicted by the amplitude of the R wave and associated direction of the T wave [1]. The objective is to initially predict ventricular hypertrophy by bipolar limb lead system without any chest limbs. We took the ECG database of 48 patients of Left Ventricular Hypertrophy (LVH), 18 patients of Right Ventricular Hypertrophy (RVH), and 48 normal patients collected by the same device (CS-12) of the same hospital. We compared the ECG of both LVH and RVH patients and noted that the amplitude of Lead-I of RVH patients is not that much distinguishable with normal ECG whereas it is highly distinguishable with the LVH patient [1].