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www.jcrpjournal.com Obstructive Sleep Apnea Screening in CR / 1
ORIGINAL INVESTIGATION
Author Affiliations: Toronto Rehabilitation
Institute/University Health Network,
Toronto, Ontario, Canada.
All authors have read and approved the
article.
The authors declare no conflicts of
interest.
Correspondence: Susan Marzolini, PhD,
Toronto Rehabilitation Institute, 347
Rumsey Rd, Toronto, ON M4G1R7,
Canada (Susan.marzolini@uhn.ca).
K E Y W O R D S
cardiac rehabilitation
obstructive sleep apnea
■ PURPOSE: Obstructive sleep apnea (OSA) is prevalent in patients with car-
diovascular disease and is often undiagnosed. The purpose of this
study was to determine the utility of communicating OSA risk with the
patients in a diabetes and cardiac rehabilitation program (CRP) and
primary care physicians.
■ METHODS: Following an OSA education session, 295 patients in diabetes
and CRPs were screened for OSA and daytime sleepiness by STOP-
BANG and Epworth Sleepiness Scale questionnaires. Letters were sent
to patients at high risk or noncompliant with continuous positive air-
way pressure (CPAP) treatment and their physicians. Follow-up ques-
tionnaires were sent to patients 6 months later.
■ RESULTS: Of the 295 patients screened, 16.6% (n = 49) had an OSA diag-
nosis and had been prescribed CPAP. A smaller proportion patients in
the diabetes program than in the CRP had discontinued CPAP (22.2%
vs 45.2%; P = .03) with discomfort being the greatest barrier. Three of
the 7 patients (42.9%) who had contact with their physician resumed
CPAP. Of the remaining 246 patients who scored high on ≥1 ques-
tionnaire (77.6%; n = 191) and returned the 6-month questionnaire
(53.9%; n = 103), communication of risk assessment resulted in
49.5% (n = 51) of patients consulting with their physician. Of those,
half were referred for polysomnography. All were diagnosed with
OSA.
■ CONCLUSION: More than three quarters of patients in diabetes and CRPs
scored high on ≥1 questionnaire suggesting signs/symptoms of OSA.
However, only 16.6% were prescribed CPAP and compliance to treat-
ment was poor (63.3%). Education and communication of OSA risk
with patients and physicians resulted in a de novo diagnosis in at least
1 of 10 patients screened and 16.7% restarted CPAP.
Utility of Screening for Obstructive
Sleep Apnea in Cardiac Rehabilitation
Susan Marzolini, PhD; Michael Sarin, MD; Jaan Reitav, PhD; Monique Mendelson, PhD; Paul Oh, MD
Obstructive sleep apnea (OSA) is characterized by
repetitive periods of breathing cessation (apnea) or
partial collapse of the upper airway and significant
reductions of airflow (hypopnea), resulting in arousal
and hypoxia during sleep.
1,2
Symptoms associated
with OSA may include excessive daytime sleepiness,
witnessed apneas, snoring, morning headaches, dry
mouth, nocturia, as well as impaired concentration
and mood. There is increasing awareness of the asso-
ciation between OSA, cardiovascular disease (CVD),
DOI: 10.1097/HCR.0000000000000186
and diabetes, both in terms of its role as a risk factor
and the beneficial effects of treatment with continuous
positive airway pressure (CPAP).
3-5
However, although
there is a high prevalence of coexisting OSA in people
with CVD and diabetes, it often goes undiagnosed.
6-13
This is of clinical significance as observational and
cross-sectional cohort studies have shown that there
is an association between the severity of untreated
OSA and hypertension, coronary artery disease,
stroke, and poor glycemic control.
13-16