CASE REPORT PEER REVIEWED | OPEN ACCESS www.edoriumjournals.com International Journal of Case Reports and Images (IJCRI) International Journal of Case Reports and Images (IJCRI) is an international, peer reviewed, monthly, open access, online journal, publishing high-quality, articles in all areas of basic medical sciences and clinical specialties. Aim of IJCRI is to encourage the publication of new information by providing a platform for reporting of unique, unusual and rare cases which enhance understanding of disease process, its diagnosis, management and clinico-pathologic correlations. IJCRI publishes Review Articles, Case Series, Case Reports, Case in Images, Clinical Images and Letters to Editor. Website: www.ijcasereportsandimages.com Idiopathic orofacial granulomatosis: A case report Dhupar Anita, Carvalho Karla M., Spadigam Anita, Syed Shaheen ABSTRACT Introduction: Orofacial granulomatosis (OFG) is a lesser known disease entity, which presents a confounding spectrum of oral manifestations. It is a non-specific granulomatous inflammation caused by an elusive etiopathogenesis. It usually manifests as persistent and/or recurrent upper and/or lower labial enlargement. The clinical features, both extra- oral and intra-oral, are highly variable and at times, insidious. This disease can be both cosmetically and functionally debilitating. Case Report: This is a report of an unusual case of orofacial granulomatosis which presented as a persistent severe generalized gingival enlargement in a nine-year-old child. There was no evidence of an underlying allergic or systemic cause. Surgical intervention (i.e., gingivectomy) showed no alleviation of symptoms. Conclusion: Making a prompt and precise diagnosis of orofacial granulomatosis is often challenging, however complete remission is possible with targeted therapy. (This page in not part of the published article.)