1 Molecular basis of the selective binding of MDMA enantiomers to the alpha4beta2 nicotinic receptor subtype: synthesis, pharmacological evaluation and mechanistic studies Salomé Llabrés, 1,& Sara García-Ratés, 2,& Edgar Cristóbal-Lecina 3 Antoni Riera, 3 José Ignacio Borrell, 4 Jorge Camarasa, 2 David Pubill, 2 F. Javier Luque, 1 Elena Escubedo 2,* 1 Department of Physical Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, Campus de l‟Alimentació Torribera, University of Barcelona. Avda. Prat de la Riba 171, Santa Coloma de Gramenet, E-08921 Barcelona, Spain 2 Department of Pharmacology and Therapeutic Chemistry and Institut of Biomedicine (IBUB), Faculty of Pharmacy, University of Barcelona, Nucli Univ. Pedralbes, E-08028 Barcelona 3 Institute for Research in Biomedicine (IRB Barcelona), Baldiri i Reixac, 10, 08028 Barcelona, Spain 4 IQS School of Engineering, Universitat Ramon Llull, Via Augusta 390, E-08017 Barcelona, Spain & These authors have contributed equally to this work. * Corresponding author: E-mail: eescubedo @ ub.edu; Phone: +34 934024531 *Revised Manuscript Click here to view linked References