UNCORRECTED PROOF only 2 cases (TS ≥ 2.2 cm). Frozen section biopsy was positive in 4 cases (11.7%) and the procedure was aborted. SLN sensitivity in detection of metastasis was 100% for TS less than 2.2 cm, negative lymphovascular space involvement (LVSI), and DOI b 5 mm. Median follow-up was 11.2 months (range 1-24) and all patients remain without evidence of disease. Conclusions: Our findings confirm the clinical significance of SLN mapping in minimizing systematic lymphadenectomy and support less radical surgery of the parametrium with greater safety in cases with small tumors. However, this study establishes our technique as feasible and adequate in early-stage cervical cancer. doi:10.1016/j.ygyno.2016.04.102 71 - Featured Poster Session Obesity significantly reduces the sentinel lymph node detection rate in women with endometrial cancer P.T. Soliman a , A.M. Nick a , C.C.L. Sun a , S. Dioun b , N. Pal a , M. Abdelwahab a , M. Frumovitz a , P.T. Ramirez a , K.H. Lu a , S.N. Westin a . a The University of Texas MD Anderson Cancer Center, Houston, TX, USA, b Baylor College of Medicine, Houston, TX, USA Objectives: The role of sentinel lymph node (SLN) mapping continues to evolve in the surgical management of endometrial cancer. The reported overall detection rate of any SLN is 80%, with a bilateral SLN detection rate of nearly 60%. The purpose of this study was to determine if patient-specific factors affect the ability to identify SLNs in women with newly diagnosed endometrial cancer. Methods: Prospective data collected as part of 2 ongoing clinical trials evaluating SLN in endometrial cancer were reviewed. Clinical characteristics such as age, body mass index (BMI), previous abdom- inal surgery, uterine size, presence of fibroids, adenomyosis, grade, and depth of invasion were collected. Identification of SLN was classified as any, unilateral, or bilateral. Univariate logistic regression was used to calculate odds ratios. Results: Two hundred and forty-six patients underwent attempted SLN mapping between April 2013 and August 2015. Median age and BMI were 60.5 years (range, 23.5–87.0) and 33.8 kg/m 2 (range, 15.8– 68.3), respectively. At least 1 SLN was detected in 79.7% (194/246) of patients; of these, 59.8% (116) were bilateral, 39.2% (76) were unilateral, and 1% (2) were paraaortic only. Indocyanine green was the most common dye used (n = 169, 68.7%), followed by blue dye (n = 63, 25.6%) and blue dye + technetium (n = 12, 4.9%). Surgical approach varied with 39.4% (97) robotic, 50.0% (123) laparoscopy, and 10.6% (26) laparotomy. Compared with normal weight women, obese women were significantly less likely to have an SLN (odds ratio [OR] 0.07, 95% CI 0.01–0.56, P = 0.01). With each increase in BMI by 1 kg/m 2 , there was a 5% decrease in SLN detection (OR 0.95, 95% CI 0.92–0.99, P = .004). There was no difference in SLN detection rates based on age, previous surgery, uterine size, fibroids, adenomyosis, grade, or depth of invasion. Conclusions: Overall SLN detection rate was 79.7%. Obesity was the only patient-specific factor that decreased the likelihood of identi- fying a SLN. This should be considered when counseling patients about SLN biopsy for endometrial cancer. doi:10.1016/j.ygyno.2016.04.103 72 - Featured Poster Session Feasibility study of indocyanine green for sentinel lymph node mapping in early-stage cervical cancer A.L. Beavis a , S. Salazar-Marioni b , A.K. Sinno a , R.L. Stone a , A. Nickles Fader a , A. Santillan c , E.J. Tanner III a . a Johns Hopkins Hospital, Baltimore, MD, USA, b University of Monterrey, San Pedro Garza Garcia, Mexico, c Cancer Care Centers of South Texas, San Antonio, TX, USA Objectives: Standard techniques for sentinel lymph node (SLN) mapping in cervical cancer remain unclear, with limited data on the use of indocyanine green (ICG). We sought to determine the feasibility and mapping rate of SLNs with intracervical injection of ICG in patients with cervical cancer. Methods: Women with early-stage cervical cancer (stage IA1–IB2) underwent SLN mapping with ICG during initial surgical manage- ment, either with robotic-assisted radical hysterectomy (RA-RH) or fertility-sparing surgery at 2 high-volume centers from October 2012 to August 2015. ICG was injected peritumorally at the 3 and 9 o'clock positions of the cervical stroma. Bilateral pelvic lymphadenectomy was concurrently performed for all patients, except in cases in which extracervical disease was identified intraoperatively. All clinically enlarged lymph nodes were removed. Results: Twenty-three women with a median age of 47 years and body mass index of 28.4 were included: 17 (74%) had squamous cell carcinoma and 6 (26%) had adenocarcinoma. Most patients (74%) had stage IB disease. Most patients (91%) underwent RA-RH, 1 patient underwent cold knife cone for fertility preservation, and in 1 case, the RH was aborted. Clinical tumor size ranged from microscopic to 4.5 cm, with a median of 1.5 cm. SLN mapping was successfully performed in 22 cases (96%), of which 91% demonstrated successful bilateral mapping. Seven tumors were 2 cm or greater, and 100% had successful bilateral mapping. A median of 2 SLNs were removed from each hemi-pelvis. SLNs were most commonly identified in the hypogastric (48%), external iliac (20%), obturator (14%), common iliac (8%), and para-aortic (8%) regions. In 2 cases, lymph node metastasis was identified. In 1, bilateral SLN mapping was successful, and frozen section of the sentinel nodes was positive at the time of surgery. In another, bilateral SLN mapping was successful and the SLNs were negative; however, enlarged nodes were removed because of their suspicious appearance at the time of surgery and found to have metastasis. Conclusions: SLN mapping with ICG is feasible and has high detection rates in early-stage cervical cancer. Removal of clinically suspicious nodes is critical regardless of SLN mapping success. Further studies are needed to determine if SLN alone can replace lymphadenectomy in women with early-stage cervical cancers in the absence of clinically suspicious lymph nodes. doi:10.1016/j.ygyno.2016.04.104 73 - Featured Poster Session Single-port laparoscopy and PINPOINT mapping of sentinel lymph nodes with indocyanine green (ICG) in endometrial carcinoma C.M. Michener a , A.M. Jernigan b , K. Levinson c . a Cleveland Clinic, Cleveland, OH, USA, b Cleveland Clinic Foundation, Cleveland, OH, USA, c Johns Hopkins Hospital, Baltimore, MD, USA Objectives: To present the first report and feasibility of single port laparoscopy (SPL) for sentinel lymph node (SLN) mapping using indocyanine green (ICG) in women with endometrial carcinoma (EC). Methods: Women with EC were prospectively followed under an institutional review board–approved protocol for SLN mapping as part of their initial surgical management. An injection of 0.5 mL of a 500 μg/ mL solution was given superficially, then 1-cm deep at the 3 and 9 o'clock positions of the cervix. All patients subsequently underwent SPL with SLN mapping and hysterectomy with additional lymphade- nectomy as indicated based on Mayo Clinic criteria for staging. Results: Seven women with a median age of 59 years underwent SPL with hysterectomy/salpingo-oophorectomy and SLN mapping. Median body mass index and prior surgeries were 28.7 and 1, respectively. Abstracts / Gynecologic Oncology 141 (2016) 2–208 31