olitary fibrous tumor (SFT) was first described as a primary spindle
cell tumor of the pleura in 1931 and has been subsequently reported
in extra-pleural sites.
1-4
Orbit is an uncommon location for SFT,
where diagnosis is challenging and requires immunohistochemical analy-
sis along with clinical, radiological and pathological evaluation. Besides,
the nomenclature of specialized fibroblastic tumors of the orbit has
changed recently. CD34 immunopositive fibroblastic neoplasms, which
were previously classified as separate entities, are now comprised as SFT.
5
In this case report, we present a case of an orbital SFT treated with com-
plete surgical excision.
Turkiye Klinikleri J Ophthalmol 2017;26(3):219-22
219
An Uncommon Orbital Neoplasm:
Solitary Fibrous Tumor: Case Report
ABSTRACT The purpose of this case report is to present an intraconally located orbital solitary fi-
brous tumor, an uncommon fibroblastic tumor of the orbit which has diagnostic challenges. A 33
years old female patient presented with three years of slowly progressive mass and proptosis of the
left eye. Magnetic resonance imaging demonstrated a well-defined, strongly enhancing intraconal
orbital mass. Histopathological and immunohistochemical analysis following en - bloc removal of
the lesion revealed a mesenchymal tumor showing strong positivity for CD34 and Vimentin. The
diagnosis was solitary fibrous tumor. Although uncommon, solitary fibrous tumor should be kept
in mind in the differential diagnosis of a well-defined orbital mass associated with slowly progres-
sive proptosis.
Keywords: Exophthalmos; solitary fibrous tumors; antigens, CD34; immunohistochemistry;
orbital neoplasms
ÖZET Bu makalede, yavaş ilerleyici propitozisin az rastlanan bir sebebi olan intrakonal yerleşimli
bir orbital soliter fibröz tümör (SFT) olgusunu sunmayı amaçladık. Otuz üç yaşında kadın hasta,
sol gözünde 3 yıldır yavaş büyüyen kitle ve proptozis şikayeti ile başvurdu. Magnetik rezonans gö-
rüntülemede, iyi sınırlı, yoğun kontrast tutan intrakonal kitle tespit edildi. Kitle lateral orbitotomi
yoluyla bütünüyle eksize edildi. Çıkarılan 31x31x35 mm boyutlarındaki kitle, immunohistokimyasal
analizi de içeren histopatolojik inceleme sonucunda, güçlü CD-34 ve Vimentin pozitifliği gösteren
mezenkimal tümör olarak tanımlandı. Bu bulgular ışığında olguya benign orbital SFT tanısı ko-
nuldu. Yavaş ilerleyici proptozise sebep olan iyi sınırlı orbital kitlelerin ayırıcı tanısında SFT akılda
tutulmalıdır.
Anahtar Kelimeler: Ekzoftalmus; soliter fibröz tümörler; antijenler, CD34; immünohistokimya;
orbita neoplazileri
Okan TOYGAR,
a
Levent AKÇAY,
b
Özge YABAŞ KIZILOĞLU,
a
Baha TOYGAR,
a
Özlem YAPICIER,
c
Mustafa Kemal DEMİR
d
Departments of
a
Ophthalmology,
c
Pathology,
d
Radiology,
Bahçeşehir University Faculty of Medicine,
b
Clinic of Ophthalmology,
Dünyagöz Research Hospital,
İstanbul
Geliş Tarihi/Received: 23.10.2015
Kabul Tarihi/Accepted: 23.01.2016
Yazışma Adresi/Correspondence:
Özge YABAŞ KIZILOĞLU
Medical Park Göztepe Hospital,
Clinic of Ophthalmology, İstanbul,
TÜRKİYE/TURKEY
ozgeyabas@hotmail.com
This case report has been presented
as a poster at the 48
th
Meeting of the
Turkish Ophthalmology Society,
5-9 November 2014, Antalya.
Copyright © 2017 by Türkiye Klinikleri
OLGU SUNUMU
DOI: 10.5336/ophthal.2015-46936