s — ª RES R t t r s { s s t r t r s x t r t r s r t r t r ª ª w ª ª t w Pr edictivevalueofcontr olofCOPDforriskofexacerbations Aninternationalpr ospectivestudy Marc Miravitlles Pawel Sliwinski Chin Kook Rhee Richard W Costello V ictoria Carter Jessica HY T an Therese Sophie Lap p erre Bernardino Alcazar Caroline Gouder Cristina Esquinas Juan Luis GarcíaRivero Anu Kemppinen Augustine T ee Miguel RomanRodríguez Juan José Soler Cat aluña David B Price on b ehalf of the RespiratoryEf fectivenessGroupREG PneumologyDepartment UniversityHospital V all d’Hebron V all d’Hebron ResearchInstituteVHIR BarcelonaSpain CIBERde Enfermedades Resp iratorias CIBERES Spain ndDepartmentofRespiratoryMedicineInstituteofT uberculosisandLungDiseasesW arsaw Poland DivisionofPulmonary Aller gyandCriticalCareMedicineDepartmentofInternalMedicineSeoulStMarysHospitalCollegeofMedicine TheCatholicUniversityofKoreaSeoulRepublicofKorea DepartmentofRes piratoryMedicineRoyalColleg eofSur geonsDublinIreland OptimumPatientCareCambridgeUK SingaporeGeneralHospitalSingapore DukeNationalUniversityofSingaporeMedicalSchoolSingapore Bispebjer g HospitalCopenhagenDenmark RespiratoryDepartmentHo spitaldeAlta Resolució n deLojaSpain DepartmentofRespiratoryMedicine MaterDeiHospitalMalta Public Health Mental Maternal and Child Health Nursing Departament Facu lty o f Medicin e and Health Scienc es University of Barcelona Spain HospitalComarcaldeLaredoCantabria Spain RespiratoryandCriticalCareMedicine ChangiGeneralHospitalSingapore Primary Healthcare CenterSon P isà IBSalutPalma Baleares Spain PneumologyDepartmentHospital Arn au de V ilanova V alenci aSpain CentreofAcademicPrimaryCareUniversityofAberdeenUK ObservationalandPragmaticResearchInstituteSingapore