Journal of Accounting and Investment Vol. 25 No. 1, January 2024 Article Type: Research Paper Antecedents of perceived usefulness on the use of electronic hospital management information systems Adinda Adia Putri 1 , Oscar Jayanagara 1 * and Dwi Julianingsih 2 Abstract Research aims: This study aims to analyze the factors that influence SIMRS and examine the mediating effect of perceived ease of use on the factors that affect SIMRS. Design/Methodology/Approach: This explanatory research used a quantitative approach through survey methods. The population in this study was doctors practicing in the outpatient polyclinic of XYZ Hospital, totaling 80 doctors using the total sampling. Data collection techniques employed a scale and analyzed utilizing Smart Partial Least Square (PLS). Research findings: According to the research findings, all examined indicators were found to be positively and substantially correlated with perceived ease of use by the following variables: computer self-efficacy, trustworthiness, technological risk, facilitating conditions, and degree of openness. Although all but the degree of openness exhibited a significant correlation with perceived usefulness, the remaining indicators did not. In relation to perceived usefulness, all factors exhibited a positive and statistically significant association with perceived ease of use as a mediator. Practical and Theoretical Contribution/Originality: In terms of practical and theoretical contributions, these findings offer valuable insights for hospitals, emphasizing the importance of enhancing doctors' knowledge, openness, and confidence in adopting SIMRS technology. Recommendations offered include increasing computer literacy among doctors, mitigating risks associated with SIMRS, and improving access to healthcare services. Research limitation: In this case, the research limitation stems from the need to explore further additional characteristics, such as computer self-efficacy, trustworthiness, technological risk, facilitating conditions, and perceived ease of use, as they may impact perceived usefulness across various variables. Future research should expand its scope and population, employing comprehensive data collection techniques to maximize research outcomes. Keywords: SIMRS; Technology Acceptance Model (TAM); Unified Theory of Acceptance and Use of Technology (UTAUT) Introduction In recent years, the Indonesian government has significantly promoted the use of Information and Communication Technology (ICT) in various sectors. Information technology can be used to assist organizations in processing, storing, and transforming data into the information they need (Antoni et al., 2017). It becomes the main facilitator for organizational activities, AFFILIATION: 1 Department of Management, Universitas Pelita Harapan, Banten, Indonesia 2 Department of Management Retail, Universiy of Raharja, Banten, Indonesia *CORRESPONDENCE: Oscar.fe@uph.edu DOI: 10.18196/jai.v25i1.19120 CITATION: Putri, A. A., Jayanagara, O., & Julianingsih, D. (2024). Antecedents of perceived usefulness on the use of electronic hospital management information systems. Journal of Accounting and Investment, 25(1), 387- 412. ARTICLE HISTORY Received: 12 Jul 2023 Revised: 19 Jul 2023 30 Aug 2023 16 Sep 2023 Accepted: 05 Feb 2024 This work is licensed under a Creative Commons Attribution-Non-Commercial- No Derivatives 4.0 International License JAI Website: