Accepted Manuscript Local delivery of adenosine receptor agonists to promote bone regeneration and defect healing Christopher D. Lopez, Jonathan M. Bekisz, Carmen Corciulo, Aranzazu Mediero, Paulo G. Coelho, Lukasz Witek, Roberto L. Flores, Bruce N. Cronstein PII: S0169-409X(18)30149-2 DOI: doi:10.1016/j.addr.2018.06.010 Reference: ADR 13320 To appear in: Advanced Drug Delivery Reviews Received date: 20 October 2017 Revised date: 8 May 2018 Accepted date: 12 June 2018 Please cite this article as: Christopher D. Lopez, Jonathan M. Bekisz, Carmen Corciulo, Aranzazu Mediero, Paulo G. Coelho, Lukasz Witek, Roberto L. Flores, Bruce N. Cronstein , Local delivery of adenosine receptor agonists to promote bone regeneration and defect healing. Adr (2018), doi:10.1016/j.addr.2018.06.010 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.