Novel Fluorophores: Efficient Synthesis
and Photophysical Study
Gil Tae Hwang, Hyung Su Son, Ja Kang Ku, and Byeang Hyean Kim*
Center for Integrated Molecular Systems, Department of Chemistry,
DiVision of Molecular Life Science, Pohang UniVersity of Science and Technology,
Pohang 790-784, Korea
bhkim@postech.ac.kr
Received June 4, 2001
ABSTRACT
We have synthesized novel fluorophores by using Sonogashira reactions of 1,4-bis(dibromovinyl)benzene and 2,5-bis(dibromovinyl)thiophene
with various aromatic bromides. The emission maxima of these fluorophores vary from the indigo blue to the reddish-orange region, depending
on the structures of aromatic nuclei and peripheral moieties.
Organic molecules with high photoluminescence efficiencies
have recently attracted increasing attention in various
research fields as advanced materials for electronic and
photonic applications.
1,2
Thus, it is important to synthesize
efficiently novel fluorophores that are amenable to further
chemical functionalization or modification, which in turn is
essential to obtain materials with tunable optoelectronic
properties.
1,1-Dibromo-1-alkenes 1 are conveniently prepared by the
procedure of Corey and Fuchs.
2
They can be converted to
(Z)-1-bromo-1-alkenes 2,
3
(Z)-1-aryl(alkenyl)-1-bromo-1-
alkenes 3,
4
1,1-diaryl(alkenyl)-1-alkenes 4,
5c
1-aryl(alkenyl)-
1-alkynes 5,
3,5c
and 1,3-diynes 6
6
(Scheme 1). However, few
studies on the Sonogashira reaction
7
of 1,1-dibromo-1-
alkenes have been reported. Furthermore, to the best our
knowledge, there is no precedent for the synthesis of
fluorophores by using this approach, which may provide
(1) (a) Seminario, J. M.; Tour, J. M. In Molecular ElectronicssScience
and Technology; Aviran, A., Ratner, M., Eds.; New York Academy of
Science: New York, 1998. (b) Mu¨llen, K., Wegner, G., Eds. In Electronic
Materials: The Oligomer Approach; Wiley-VCH: New York, 1998.
(2) For recent reviews, see: (a) de Silva, A. P.; Gunaratne, H. Q. N.;
Gunnlaugsson, T.; Huxley, A. J. M.; McCoy, C. P.; Rademacher, J. T.;
Rice, T. E. Chem. ReV. 1997, 97, 1515. (b) Kraft, A.; Grimsdale, A. C.;
Holmes, A. B. Angew. Chem., Int. Ed. 1998, 37, 402. (c) Sheats, J. R.;
Chung. Y. L.; Roitman, D. B.; Stocking, A. Acc. Chem. Res. 1999, 32,
193. (d) Yamaguchi, S.; Endo, T.; Uchida, M.; Izumizawa, T.; Furukawa,
K.; Tamao, K. Chem. Eur. J. 2000, 6, 1683.
(3) Corey, E. J.; Fuchs, P. L. Tetrahedron Lett. 1972, 4831.
Scheme 1
ORGANIC
LETTERS
2001
Vol. 3, No. 16
2469-2471
10.1021/ol0162264 CCC: $20.00 © 2001 American Chemical Society
Published on Web 07/19/2001