Online ISSN : 2252-0554 Iranian Journal of Veterinary Medicine Volume 13- Issue 04 The Clinical Comparison of Intraosseous and Intravenous Anesthesia (Thiopental-Na) in Pigeon Copyright © 2019. This is an open-access article distributed under the terms of the Creative Commons Attribution- 4.0 International License which permits Share, copy and redistribution of the material in any medium or format or adapt, remix, transform, and build upon the material for any purpose, even commercially. _________________________________________________________________________________________ Correspondence Mohammad Reza Aghchelou, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran Tel: +98(543) 1232250, Fax: +98(543)1232251, Email: mraghchelou@gmail.com Received: 2019-05-21 Accepted: 2019-09-03 How to Cite This Article Bakhshi, M., Aghchelou, M. R., & Saadati, D. (2019). The Clinical Comparison of Intraosseous and Intravenous Anesthesia (Thiopental-Na) in Pigeon. Iranian Journal of Veterinary Medicine, 13(4), 401-409. 1 Graduated from the Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran 2 Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran 3 Department of Food Hygiene and Quality Control, Faculty of Veterinary Medicine, University of Zabol, Zabol, Iran Samane Bakhshi 1 , Mohammad Reza Aghchelou *2 , Dariush Saadati 3 Abstract BACKGROUND: Intraosseous injection is a way of administration of drugs. OBJECTIVES: The clinical comparison of intraosseous and intravenous injection of Thiopental-Na. METHODS: First, all birds (twenty-six healthy pigeons) were split out into two groups randomly. Group A received 20 mg kg-1 Thiopental-Na by intraosseous route and group B by intravenous route. After one week that iInt J Radiat Biol, s needed for washing out the drug, group A received 20 mg kg-1 Thiopental-Na by intra- venous route and group B by intraosseous route. The respiratory rate (fR), heart rate (HR) and cloacal tempera- ture (T) were measured before (0 minute) and 1, 5, 10, 20 and 30 minutes after anesthetic drug administration. Reaction to injection, number of efforts for injection, duration to onset of anesthesia and different scores of anesthesia were checked. Returning from anesthesia in the two groups was recorded and compared. RESULTS: Statistical assessment showed anesthesia onset in the method of intravenous injection was signifi- cantly less than the method of intraosseous injection (P=0.003), and the fR in two groups was different in 1 min after drug administration (P=0.036). There was not statistically difference in other minutes for fR, HR and T in two groups (P >0.05). Statistical analysis showed that there were no significant differences in terms of number of efforts for anaesthetizing as well as anesthesia stage in both methods in different minutes (P>0.05). Also, no significant alterations were recorded for recovery time for both groups. There was not any visible lameness or pain for intraosseous route after recovery. CONCLUSIONS: Intraosseous anesthesia injection in birds is a practicable and fast procedure and compara- ble with intravenous route. KEYWORDS: anesthesia, intraosseous injection, intravenous injection, Thiopental-Na, pigeon ijvm.2019.269704.1004942 Original Article