266 Introduction The presence of clinical features, symptoms, treatment and prevalence of oral lesions in children and adolescents may be different from that of adults (1-4). Reactive lesions comprise a group of connective fibrous tissue lesions that commonly occur in the mouth as a result of trauma (5). Regardless of dental caries, periodontal disease and periapical inflammatory lesions, hyperplastic lesions represent the most common oral mucosal lesions in humans (6,7). These lesions are classified as pyogenic granuloma, peripheral ossifying fibroma, and peripheral giant cell granuloma and irritation fibroma. Chronic local irritation is the most frequently etiologic factor of all this lesions. However, these lesions can show dramatic different ABSTRACT The presence of clinical features, symptoms, treatment and prevalence of oral lesions in children and adolescents may be different from that of adults. The aim of this study was to evaluate the clinical and pathological features of inflammatory/reactive oral lesions in children and adolescents from 1996 to 2013. Patient records of the Department of Oral Pathology of Kerman dental school, Iran during 17 years were reviewed. Demographic data, clinical diagnosis and histopathologic features were retrieved. The data were analyzed using SPSS 20 soft ware. Chi-square or t-test was used for groups comparison. Significant level was set at 0.05. Out of 1561 records, 241(14.59%) were between 0 and 18 year- old and 102 (42.32%) cases of inflammatory/reactive lesions were seen. The most common lesion was pyogenic granuloma. Most of the lesions were located in the maxilla (p=0.028).There was significant differences between age and frequency of lesions (p=0.008). In 63.2%of cases clinical features were compatible with histopathological diagnosis. Based of the findings of the current study, inflammatory/reactive lesions were the most common oral biopsied lesions. KEYWORDS Adolescents, Children, Oral biopsied lesions, Reactive lesions, inflammatory lesions A 17-year clinical and pathological evaluation of inflammatory/reactive oral lesions in children and adolescents Molouk Torabi 1 , Jahangir Haghani 1 , Maryam Rad 2 ,Hamid Reza Poureslami 1 *, and San Ali Karimi Afshar 1 1 Kerman Oral and Dental Diseases Research Center and Department of Radiology, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran 2 Kerman Oral and Dental Diseases Research Center and Oral Medicine specialist, Iran *Corresponding author ISSN: 2347-3215 Volume 3 Number 4 (April-2015) pp. 266-271 www.ijcrar.com