65 © The Author(s) 2022 S. Nundy et al., How to Practice Academic Medicine and Publish from Developing Countries?, https://doi.org/10.1007/978-981-16-5248-6_7 7 How to Think of a Research Question? 7.1 What Is a Research Question? A research question is the central theme of a scientiﬁc experiment around which everything revolves. It is a probing statement for which an answer is required. If the research question is not clear at the beginning the whole research becomes question- able and doubtful. Thus, formulating a question is the critical step towards biomedi- cal research [1]. The research question is a signpost that indicates the direction of a study [2] and is based on the gaps in our knowledge. 7.2 What Are the FINER Criteria? FINER is an acronym which help us to formulate a good research question [3]. Its expanded form is given below: F—Feasible • It is a technique that is possible to use. • There are enough patients with this illness. • Financially the project is possible. • The outcome can be measured. • The sample size will not be a problem. • The scope of the study is not too vast. The art and science of asking questions is the source of all knowledge —Thomas Berger, American Novelist (1924–2014)