© 2023 Hong Kong College of Psychiatrists. CC BY-NC-ND 4.0 East Asian Arch Psychiatry 2023;33:65-70 | https://doi.org/10.12809/eaap2258 Original Article 65 Psychometric Properties of Vietnamese Versions of the Clinician-Rated and Self-Reported Quick Inventory of Depressive Symptomatology and the Patient Health Questionnaire Ho Nguyen Yen Phi, Bui Xuan Manh, Tran Anh Ngoc, Pham Thi Minh Chau, Truong Quoc Tho, Nguyen Trung Nghia, Tran Trung Nghia, Huynh Ho Ngoc Quynh, Nguyen Tien Huy, Ngo Tich Linh, Pham Le An Abstract Objective: Major depressive disorder (MDD) is the second-most prevalent mental health condition in Vietnam. This study aims to validate the Vietnamese versions of the self-reported and clinician-rated Quick Inventory of Depressive Symptomatology (QIDS-SR and QIDS-C, respectively) and the Patient Health Questionnaire (PHQ-9), and to assess the correlations between the QIDS-SR, QIDS-C, and PHQ-9. Methods: 506 participants with MDD (mean age, 46.3 years; 55.5% women) were assessed using the Structured Clinical Interview for DSM-5. The internal consistency, diagnostic efficiency, and concurrent validity of the Vietnamese versions of QIDS-SR, QIDS-C, and PHQ-9 were determined using the Cronbach’s alpha, receiver operating characteristic curve, and Pearson correlation coefficient, respectively. Results: The Vietnamese versions of QIDS-SR, QIDS-C, and PHQ-9 demonstrated acceptable validity, with an area under the receiver operating characteristic curve of 0.901, 0.967, and 0.864, respectively. Sensitivity and specificity, respectively, were 87.8% and 77.8% for QIDS-SR and 97.6% and 86.2% for QIDS-C at the cut-off score of 6, and were 82.9% and 70.1% for PHQ-9 at the cut-off score of 4. Cronbach’s alphas for QIDS-SR, QIDS-C, and PHQ-9 were 0.709, 0.813, and 0.745, respectively. The PHQ-9 highly correlated with the QIDS-SR (r = 0.77, p < 0.001) and the QIDS-C (r = 0.75, p < 0.001). Conclusion: The Vietnamese versions of the QIDS-SR, QIDS-C, and PHQ-9 are valid and reliable tools for screening of MDD in primary healthcare settings. Key words: Depressive disorder, major; Patient Health Questionnaire; Primary health care; Vietnam Ho Nguyen Yen Phi, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Bui Xuan Manh, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Tran Anh Ngoc, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Pham Thi Minh Chau, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Truong Quoc Tho, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Nguyen Trung Nghia, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam; Mental Health Unit, Hoan My Sai Gon Hospital, Ho Chi Minh City, Vietnam Tran Trung Nghia, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Huynh Ho Ngoc Quynh, Department of Health Education and Psychology in Medicine, Faculty of Public Health, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Nguyen Tien Huy, School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan Ngo Tich Linh, Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam Pham Le An, The Center of Training Family Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam; Department of Psychiatry, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam; Mental Health Unit, Hoan My Sai Gon Hospital, Ho Chi Minh City, Vietnam Address for correspondence: Dr Ho Nguyen Yen Phi, Department of Psychiatry, University of Medicine and Pharmacy at Ho Chi Minh City, Vietnam. Email: honguyenyenphi@ump.edu.vn Submitted: 2 December 2022; Accepted: 5 May 2023 Introduction Vietnam is a lower-middle-income country with a chronic shortage in mental healthcare resources. Although major depressive disorder (MDD) is the second-most common mental health condition in Vietnam, with a prevalence of 2.8%, 1 the estimated number of psychiatrists per 100 000 Vietnamese people is 0.35. 2 Additionally, as a result of internalised stigma, 3 associated somatic symptoms, 4,5 and co-occurring chronic physical conditions, 6,7 patients with mental health problems are more likely to seek care at primary healthcare centres (PHCs) rather than specialist clinics. However, PHCs lack human resources to recognise patients with MDD, 8,9 who therefore have been underdiagnosed