Effect of Active and Early Possible Organ and Tissue Donor Detection in the Emergency Room in a University Hospital Daniel Budoy*, Camino Rodriguez-Villar, David Peña, Ferran Vizcaino, Sandra Saavedra, Marc Bohils, Magda Quijada, Jose Manuel de la Cruz, David Paredes-Zapata, Angel Ruiz, Rebeca Roque, Xavier Garcia, and Ramon Adalia Bartolome Donation and Transplant Coordination Section, Hospital Clinic, University of Barcelona, Barcelona, Spain ABSTRACT Purpose. The emergency room of the hospital is the gateway for patients with severe brain damage due to neurologic or cardiac conditions such as stroke or cardiac arrest. The main purpose is to design an active registry of patients, in the emergency room, to facilitate the detection and follow-up of potential donors according to their clinical evolution. Material and Methods. This is a 1-year prospective study from May 2017 to May 2018 with a register for detection of patients admitted to the emergency room with severe brain damage (Glasgow Coma Scale score  8), with active follow-up until hospital discharge, who might have died or otherwise become possible organ and tissue donors. Results. One hundred sixty-six (107 men and 59 women) patients met the inclusion criteria: (1) 30.7% recovered from cardiac arrest; (2) 31.3% from stroke; (3) 16.9% from traumatic brain injury and multiple trauma; (4) 10.2% had decreased level of consciousness; (5) 4.8% had other cardiac conditions; and (6) 6.0% had other diagnoses. Seventy-seven out of 166 patients (46.4%) were evaluated as possible organ and tissue donors, with 37 out of 77 (48.0%) of the possible donors becoming real donors. This means that 37 out of 166 (22.3%) of the possible donors admitted to the emergency room became real donors. Twenty-two out of 77 of the patients (28.6%) evaluated had clinical contraindications for donation and in 18 out of 77 (23.4%), there was family refusal for any kind of organ or tissue donation. This record allowed the generation of the following organs and tissues: 4 hearts, 19 livers, 14 lungs, 52 kidneys, 2 pancreata, 29 corneas, 19 donations of bone allografts, 15 donations of skin tissue, 14 donations of valvular allografts, and 11 vascular allografts. Conclusions. The early and active possible donors registry at the emergency room has facilitated early detection and allow adequate follow-up and evaluation of possible organ and tissue donors. S PAIN is 1 of the countries with the highest rate of organ donation worldwide, reaching 47 donors per million population in 2017, in comparison with donation rates in other countries: Portugal (34.1 donors per million popula- tion), the United States (31.7 donors per million popula- tion) Canada (21.9 donors per million population) and Australia (20.8 donors per million population) among others, according to the 2017 Newsletter Transplant publi- cation of the Council of Europe [1]. The Spanish results are derived from a set of organizational, human, and resources measures adopted in Spain during the last 25 years in order to improve and sustain organ donation. This success in the donation and transplantation model, known as the Spanish Model, is widely described in the scientific literature with very good results [2]. *Address correspondence to Daniel Budoy, Hospital Clinic, Stair 8, Floor 4th, Barcelona, 08036, Spain. Tel: þ34627947278. E-mail: dbudoy@clinic.cat ª 2019 Elsevier Inc. All rights reserved. 230 Park Avenue, New York, NY 10169 0041-1345/19 https://doi.org/10.1016/j.transproceed.2019.08.022 Transplantation Proceedings, XX, 1e3 (2019) 1