Journal Pre-proof Plant extracts and betulin from Ligaria cuneifolia inhibit P-glycoprotein function in leukemia cells Jerónimo Laiolo, Cecilia L. Barbieri, Mariana B. Joray, Priscila A. Lanza, Sara M. Palacios, D. Mariano A. Vera, María C. Carpinella PII: S0278-6915(20)30812-7 DOI: https://doi.org/10.1016/j.fct.2020.111922 Reference: FCT 111922 To appear in: Food and Chemical Toxicology Received Date: 17 September 2020 Revised Date: 30 October 2020 Accepted Date: 8 December 2020 Please cite this article as: Laiolo, J., Barbieri, C.L., Joray, M.B., Lanza, P.A., Palacios, S.M., Vera, D.M.A., Carpinella, M.C., Plant extracts and betulin from Ligaria cuneifolia inhibit P-glycoprotein function in leukemia cells, Food and Chemical Toxicology, https://doi.org/10.1016/j.fct.2020.111922. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Elsevier Ltd. All rights reserved.