Journal Pre-proof Combination drug delivery with actively-targeted PLGA nanoparticles to overcome multidrug resistance in breast cancer Hayrettin Tonbul, Adem Sahin, Ece Tavukcuoglu, Gunes Esendagli, Yılmaz Capan PII: S1773-2247(19)30889-5 DOI: https://doi.org/10.1016/j.jddst.2019.101380 Reference: JDDST 101380 To appear in: Journal of Drug Delivery Science and Technology Received Date: 29 July 2019 Revised Date: 8 November 2019 Accepted Date: 9 November 2019 Please cite this article as: H. Tonbul, A. Sahin, E. Tavukcuoglu, G. Esendagli, Yı. Capan, Combination drug delivery with actively-targeted PLGA nanoparticles to overcome multidrug resistance in breast cancer, Journal of Drug Delivery Science and Technology (2019), doi: https://doi.org/10.1016/ j.jddst.2019.101380. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2019 Published by Elsevier B.V.