https://alqalam.utripoli.edu.ly/science/ eISSN 2707-7179 Asif et al. Alq J Med App Sci. 2020;3(2):47-53 47 Review article Effect of Social Distancing on Immune System in Fighting with SARS COVID-19 Salka Akram 1 , Naghma Shahzadi 2 , Hafiz Faizan 1 , Saqaina Anwar 1 , Muhammad Asif 1* 1 Institute of Energy and Environmental Engineering University of the Punjab Lahore 54000, Pakistan 2 Department of botany University of the Agriculture Faisalabad 38000, Pakistan. ARTICLE INFO ABSTRACT DOI: 10.5281/zenodo.3938661 * Muhammad Asif: Institute of Energy and Environmental Engineering University of the Punjab Lahore 54000, Pakistan. Mobile phone: +923047092647. Email: 03047092647asif@gmail.com Received: 5-7-2020 Accepted: 10-7-2020 Keywords: Social Distancing, Immune System, COVID-19. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). Recently, the world health organization, governments, and public health experts have highlighted the potential importance of social distancing because of COVD-19 that are beneficial for the host. Coronavirus is pandemic of respiratory illness that transfer from one person to another person through cough, sneezing, mouth droplets and touching. Asymptomatic, mildly symptomatic and pre-symptomatic are three types of coronavirus. It spread fast in the whole world. Although there is no vaccine is available in the market for coronavirus while strengthening the immune system also keeps the virus away from the host. Innate, adaptive and passive immunity has power to kills infected cells. It’s done by a cytokine storm of the adaptive immune system. Though health experts say that loneliness and self-isolation cause stress which ultimately sends your immune system into exploit but in pandemic days it will be beneficial. Cite this article: Akram S, Shahzadi N, Faizan H, Anwar S, Asif M. Effect of Social Distancing on Immune System in Fighting with SARS COVID-19. Alq J Med App Sci. 2020;3(2):47-53. INTRODUCTION Coronavirus is a family of viruses showing crown like spiked proteins on the top of the virus surface under microscope is known as coronavirus. SARS- CoV-2 (Severe Acute Respiratory Syndrome coronavirus-2) disease also named as COVID-19 (Corona virus disease 2019) by World Health Organization that first emerged in China and then become a global problem. It is a worldwide pandemic of respiratory illness, called COVID-19. There are different kinds of coronaviruses of which 4-5 types cause common diseases among humans everything from common cold to mild and moderate respiratory illness. Some of them cause diseases in animals and jump from animals to human’s species. In 2019, a novel kind of coronavirus started rapidly spreading in humans and getting a lot of attention nowadays because this is new kind of coronavirus never seen before among humans. Some theories say that it is an