https://doi.org/10.1177/00221678221136240 Journal of Humanistic Psychology 1–20 © The Author(s) 2022 Article reuse guidelines: sagepub.com/journals-permissions DOI: 10.1177/00221678221136240 journals.sagepub.com/home/jhp Original Manuscripts Harm Reduction, Humanistic Psychology, and the CRPD Gianna D’Ambrozio 1 , Lisa Cosgrove 1 , Samantha Lilly 2 , and Timothy McCarthy 1 Abstract Harm reduction, which was initially developed as a public health response to illicit drug use, has relevance to the prescription of psychotropic medication. Indeed, focusing on the agency of people who use drugs—licit or illicit— facilitates a more authentic engagement with treatment. In this paper, we show how the framework of harm reduction is congruent with the guiding principles of both humanistic psychology and the Convention on the Rights of Persons with Disabilities (CRPD). Moreover, applying a harm reduction model to psychotropic drug use raises awareness that there are risks to taking these medications, risks which are frequently glossed over because of the emphasis on medication adherence and compliance. We provide case examples of organizations that take a person-centered (vs. medication- centered) approach to people experiencing mental health crises. In their unique ways, these organizations embody the principles of harm reduction and the humanistic impulse that informs the CRPD. Keywords coercion, harm reduction, humanistic psychology, Open Dialogue, persons with disabilities, psychotropic drug use 1 University of Massachusetts Boston, USA 2 The Fulbright Program, Buenos Aires, Argentina Corresponding Author: Gianna D’Ambrozio, Doctoral Student, Department of Counseling Psychology, University of Massachusetts Boston, 100 William T. Morrissey Blvd., Boston, MA 02125, USA. Email: Gianna.Dambrozio001@umb.edu 1136240JHP XX X 10.1177/00221678221136240Journal of Humanistic PsychologyD’Ambrozio et al. research-article 2022