Clinical Case Reports and Reviews. Copy rights@ Sai P. Katke Auctores Publishing LLC – Volume 14(2)-319 www.auctoresonline.org ISSN: 2690-4861 Page 1 of 4 A Review: Applications of Chemicals on the Health Aspects of Seborrheic Dermatitis in Coastal Tropical Region Sai P. Katke * Bhavan’s Hazarimal somani college, University of Mumbai, Mumbai, Maharashtra, India. *Corresponding Author: Sai P. Katke, Bhavan’s Hazarimal somani college, University of Mumbai, Mumbai, Maharashtra, India. Received Date: June 13, 2023 | Accepted Date: June 26, 2023 | Published Date: July 05, 2023 Citation: Sai P. Katke, (2023), A Review: Applications of Chemicals on the Health Aspects of Seborrheic Dermatitis in Coastal Tropical Region, International Journal of Clinical Case Reports and Reviews, 14(2); DOI:10.31579/2690-4861/319 Copyright: © 2023, Sai P. Katke. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Abstract: Background: Knee osteoarthritis (KOA) is one of the most common degenerative diseases that can lead to disability and pain. The degenerative nature of this condition cannot be reversed or healed by any currently available treatments. Recently, there has been an upcoming interest in treating degenerative tissue disorders with minimally invasive autologous blood products. Autologous blood was preconditioned with gold particles to encourage the production of various proteins in patients’ blood. This current study investigated the safety and efficacy of pre-conditioning autologous blood with gold particles (GOLDIC®) in patients with severe knee osteoarthritis (KOA). Case presentation We report a case in which four intra-articular GOLDIC® injections were used to treat knee osteoarthritis. After a week, physiotherapy was recommended. Before and three weeks after the injections, she was assessed for her weight, the Visual Analog Scale (VAS), and the Western Ontario and McMaster University Osteoarthritis Index (WOMAC) score. GOLDIC® treatment resulted in significant weight, VAS, and WOMAC score improvements without serious side effects. Conclusion Due to the one-time blood harvesting and only four injections, the initial results demonstrated that the treatment plan is safe, less expensive, patient-friendly, and more successful at achieving compliance. This GOLDIC® treatment can significantly decrease pain and improve knee capability with overall satisfaction over a significant period. To fully validate the real potential of GOLDIC® in heterogeneous patient populations and to compare these promising results to other blood-based platforms, future randomized-controlled trials with long-term follow-up are required, despite the promising early clinical results. Key words: knee osteoarthritis; goldic; intra-articular injection; vas; womac Introduction Seborrheic dermatitis is a common skin condition that mostly affects the scalp. It causes scaly patches, itchy skin, and chronic dandruff. It primarily affects the oily areas of the body, such as the cheeks, sides of the nose, brows, ears, eyelids, and chest. This ailment can be annoying, although it is not contagious and can cause hair loss at first. Seborrheic dermatitis may resolve spontaneously. To reduce symptoms and prevent flare-ups, you may need to use medicated shampoo or other things on a long-term basis. Seborrheic dermatitis is also known as dandruff, seborrheic eczema, and seborrheic psoriasis. It is known as cradle cap when it appears in infants. Seborrheic dermatitis is a common chronic inflammatory skin condition that affects 11.6% of the general population and up to 70% of infants in their first few months of life. It can have an effect on the psyche and quality of life of people who are in a chronic relapsing cycle. Chronic skin disorders can have both physical and emotional consequences on one's life, such as discomfort, stigma, loss of self-esteem, and limitations in social activities. Some have a similar detrimental impact on quality of life to cardiovascular disease. Scalp pruritus and seborrheic dermatitis scales might contribute to social isolation. It has been reported that exposing these people to stressful conditions worsens their depressive symptoms. However, there has been Open Access Review Article International Journal of Clinical Case Reports and Reviews Sai P. Katke * AUCTORES Globalize your Research