REVIEW ON THE MOLECULAR MECHANISM OF TALIN- AND INTEGRIN-DEPENDENT CANCER INVASION Zbigniew Baster 1, * ,†,§ , Lindsay Russell 2 , Zenon Rajfur 1,3, * 1 Institute of Physics, Faculty of Physics, Astronomy and Applied Computer Science, Jagiellonian University, Kraków, Poland 2 Undergraduate Program, Barnard College of Columbia University, New York, NY, USA 3 Jagiellonian Center of Biomedical Imaging, Jagiellonian University, Kraków, Poland * Author to whom correspondence should be addressed: zbigniew.baster@nih.gov, zenon.rajfur@uj.edu.pl. † Current contact address: Cell and Developmental Biology Center, National Heart Lung and Blood Institute, NIH, Bethesda, MD 20892, USA § The modified version of a part of the presented work is included in ZB’s Ph.D. dissertation entitled Interplay between talin and β1 – integrin in cancer cells motility as a part of the procedure for obtaining a Ph.D. degree from Jagiellonian University, Kraków, Poland KEYWORDS Cancer, cell migration, talin, integrin, migrastatics