ARTICLE
Beyond the conservative hypothesis:
a meta-analysis of lexical-semantic processing
in Williams syndrome*
Carlos Romero-Rivas
1
, Sara Rodríguez-Cuadrado
1
, Lucía Sabater
2
, Pablo Rodríguez Gómez
3
,
Irene Hidalgo de la Guía
4
, Eva M. Moreno
5,6
and Elena Garayzábal Heinze
7
1
Department of Developmental and Educational Psychology, Universidad Autónoma de Madrid, Madrid,
Spain;
2
Universidad Internacional de La Rioja, Logroño, Spain;
3
Department of Psychology, Universidad Rey
Juan Carlos, Madrid, Spain;
4
Department of Spanish and Literature Theory, Universidad Complutense de
Madrid, Madrid, Spain;
5
Department of Developmental and Educational Psychology, Universidad Nacional
de Educación a Distancia, Madrid, Spain;
6
Faculty of Languages and Education, Universidad Antonio de
Nebrija, Madrid, Spain;
7
Department of General Linguistics, Universidad Autónoma de Madrid, Madrid,
Spain
Corresponding author: Carlos Romero-Rivas; Email: carlos.romeror@uam.es
(Received 15 September 2022; Revised 21 April 2023; Accepted 23 April 2023)
Abstract
Williams syndrome (WS) is a rare genetic disorder, characterised at the cognitive level by a
phenotypic pattern of relative weaknesses (e.g., visuospatial skills) and strengths (e.g., some
linguistic and nonverbal reasoning skills). In this study, we performed a systematic search
and meta-analysis on lexical-semantic processing in WS, an area of knowledge in which
contradictory results have been obtained. We found 42 studies matching our criteria, and, in
total, 78 effect sizes were included in the meta-analysis. Results showed that individuals with
WS have worse lexical-semantic skills than individuals with typical development, whether
matched by chronological or mental age. However, people with WS have better lexical-
semantic skills than people diagnosed with other cognitive disabilities. Finally, vocabulary
skills seem to be relatively spared in WS, although they present some difficulties in semantic
processing/integration, semantic memory organisation and verbal working memory skills.
Taken together, these results support a neuroconstructivist approach, according to which the
cognitive mechanisms involved in lexical-semantic processing may be modulated, even
when performance in some tasks (i.e., vocabulary tasks) might be optimal.
Keywords: Williamssyndrome;lexical-semantic processing; meta-analysis; neuroconstructivism; modularity
1. Introduction
Williams syndrome (WS; also known as Williams–Beuren syndrome) is a rare genetic
disorder that occurs in approximately 1:7,500 births (Strømme et al., 2002). It is caused
© The Author(s), 2023. Published by Cambridge University Press.
*This article was originally published with errors in the affiliations of two authors. The article has been
updated and an erratum published at https://doi.org/10.1017/langcog.2023.33.
Language and Cognition (2023), 15: 3, 526–550
doi:10.1017/langcog.2023.15
https://doi.org/10.1017/langcog.2023.15 Published online by Cambridge University Press