Page 1/31 Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids Charis Eng ( ๎€ engc@ccf.org ) Cleveland Clinic https://orcid.org/0000-0002-3693-5145 Shin-Chung Kang Nicholas Sarn Juan Venegas Masahiro Hitomi https://orcid.org/0000-0002-0937-6640 Article Keywords: Posted Date: April 25th, 2023 DOI: https://doi.org/10.21203/rs.3.rs-2787151/v1 License: ๎€ ๎€‚ This work is licensed under a Creative Commons Attribution 4.0 International License. Read Full License Additional Declarations: The authors have declared there is NO con๎€ict of interest to disclose Version of Record: A version of this preprint was published at Molecular Psychiatry on November 29th, 2023. See the published version at https://doi.org/10.1038/s41380-023-02325-3.