CASE REPORT Acute lupus choroidopathy: multimodal imaging and differential diagnosis from central serous chorioretinopathy Murat Hasanreisoglu . Gokcen D. Gulpinar Ikiz . Hamit Kucuk . Ozkan Varan . Sengul Ozdek Received: 27 October 2016 / Accepted: 27 December 2016 Ó Springer Science+Business Media Dordrecht 2017 Abstract Importance Systemic lupus erythematosus (SLE) is a thoroughly examined multi-organ disease whose common ocular complications are also well docu- mented. However, SLE choroidopathy, being a rare ocular complication, is needed to be better understood, in order to make the differential diagnosis from clinical conditions such as central serous chori- oretinopathy and provide adequate prompt treatment. Objective To provide a clear understanding for the clinical course of SLE choroidopathy by the help of enhanced depth imaging optical coherence tomogra- phy, fluorescein angiography, and indocyanine angiography. Design The study is designed as a case presentation, consisting of the physical examination results and the data gathered by the relevant screening methods for each visit, applied by the same ophthalmologists and technicians. Setting The visits were organized as same day examinations as needed, in a university hospital which works as a referral center. Keywords Systemic lupus erythematosus Á Choroidopathy Á Ocular Á Nephritis Á Central serous chorioretinopathy Á Choroid Á Retinal detachment Á Serous Introduction Systemic lupus erythematosus (SLE) is a chronic, immunologically mediated disease via pathological autoantibodies produced against components of cel- lular nucleus [1]. SLE may manifest itself as a wide variety of organ system involvement, with a wide variety of severity that proceeds with activations and remissions [2]. Ocular manifestations of SLE such as keratocon- junctivitis sicca, anterior uveitis, and lupus retinopa- thy are fairly common [3]. On the other hand, lupus choroidopathy is a rare complication of the disease and usually accompanied by devastating renal and central nervous system involvement. This acute clinical phase causes difficulties to perform adequate imaging; therefore, there are very few articles, if none, with adequate retinal and choroidal imaging of the choroidal vascular disease. Herein, we describe a SLE patient with acute choroidal involvement during a lupus nephritis attack and present fluorescein angiog- raphy (FA), indocyanine angiography (ICGA), and enhanced depth imaging optic coherence tomography (EDI-OCT) images over the course of the disease, M. Hasanreisoglu (&) Á G. D. Gulpinar Ikiz Á S. Ozdek Department of Ophthalmology, School of Medicine, Gazi University, Ankara, Turkey e-mail: rmurat95@yahoo.com H. Kucuk Á O. Varan Department of Rheumatology, School of Medicine, Gazi University, Ankara, Turkey 123 Int Ophthalmol DOI 10.1007/s10792-016-0433-y