Page 1/22 Comprehensive AI Model Development for Gleason Grading: From Scanning, Cloud-based Annotation to Pathologist-AI Interaction Xinmi Huo Bioinformatics Institute, A*STAR, Singapore KokHaur ONG Bioinformatics Institute Kah Weng Lau Department of Pathology, National University Hospital, National University Health System, Singapore Laurent Gole Institute of Molecule and Cell Biology, A*STAR, Singapore David Young Institute of Molecule and Cell Biology, A*STAR, Singapore Char Loo Tan Department of Pathology, National University Hospital, National University Health System, Singapore Chongchong Zhang Department of Pathology, The 910 Hospital of PLA, QuanZhou, China Yonghui Zhang Department of Pathology, The 910 Hospital of PLA, QuanZhou, China Xiaohui Zhu Department of Pathology, Nanfang Hospital and Basic Medical College, Southern Medical University, Guangzhou, Guangdong Province, People’s Republic of China. Longjie Li Bioinformatics Institute, A*STAR, Singapore Hao Han https://orcid.org/0000-0002-1551-2995 Haoda Lu Bioinformatics Institute, A*STAR, Singapore Gabriel Marini Bioinformatics Institute, A*STAR, Singapore Jun Xu Nanjing University of Information Science and Technology Kun Gui Bingxian Chen