Accepted Manuscript Combining Rosetta with molecular dynamics (MD): a benchmark of the MD- based ensemble protein design Jan Ludwiczak, Adam Jarmula, Stanislaw Dunin-Horkawicz PII: S1047-8477(18)30047-9 DOI: https://doi.org/10.1016/j.jsb.2018.02.004 Reference: YJSBI 7163 To appear in: Journal of Structural Biology Received Date: 5 November 2017 Revised Date: 25 January 2018 Accepted Date: 13 February 2018 Please cite this article as: Ludwiczak, J., Jarmula, A., Dunin-Horkawicz, S., Combining Rosetta with molecular dynamics (MD): a benchmark of the MD-based ensemble protein design, Journal of Structural Biology (2018), doi: https://doi.org/10.1016/j.jsb.2018.02.004 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.