Remedy Publications LLC., | http://clinicsinoncology.com/ Clinics in Oncology 2019 | Volume 4 | Article 1575 1 Pulmonary Artery Sarcoma Intimal Mimicking Embolism Lung OPEN ACCESS *Correspondence: José Aurillo Rocha, Department of Oncology, Federal University of Ceará, Nucleus of Oncology Studies, Brazil, E-mail: jaurillor@hotmail.com Received Date: 10 Jan 2019 Accepted Date: 11 Feb 2019 Published Date: 14 Feb 2019 Citation: Alencar RF, Rodrigues FP, Rocha JA, Fernandes Távora FR, de A. Meireles VSM, da Silva Leao PH. Pulmonary Artery Sarcoma Intimal Mimicking Embolism Lung. Clin Oncol. 2019; 4: 1575. Copyright © 2019 José Aurillo Rocha. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Case Report Published: 14 Feb, 2019 Case Presentation Female patient 46 years old with no prior medical history, dyspnea initiated efforts for one year, loss of weight and discrete episodes of isolated fever at the beginning there, bringing chest X-rays that period without changes in the lung fields and cardiac ; being attributed to viral infections of the upper airway and sinus disease. en sought medical attention for presenting atypical chest pain, epigastric pain, and the electrocardiogram showed T wave inversion in anterolateral wall; Cardiac catheterization was performed without visualization of coronary lesions. Chest X-ray of the time without changes. Aſter three months, the new hospital because of episodes of pre-syncope and dyspnea on moderate and small efforts. X-ray (Figure 1) showed rectification of the pulmonary artery trunk and spiky image contours in the leſt hilar region later. Transthoracic echocardiogram showed dilated right heart chambers, pulmonary artery systolic pressure of 115 mmHg and pulmonary dilated with hiperrefringente the level of the bifurcation mainly in the leſt branch, suggestive of thrombus image. Patient was conducted as Pulmonary Embolism (PE), and inciado full anticoagulation and subsequent workup cause to investigate. Ultrasonography of the lower limbs was negative for thrombus. Negative rheumatologic tests. CT angiography of the chest (Figure 2) showed macrolobulada lesion with soſt tissue coefficient fair compromise bronchial vessels in adjacency; ipsilateral pleural involvement with nodular formation; ground-glass opacities in the right middle lobe and image enhancement with the intraluminal contrast to the level of the bifurcation and the leſt pulmonary artery; suggesting thromboembolism and neoplastic lesion. Bronchial stenosis was seen on the leſt by bronchoscopy. Transbronchial biopsy performed (Figure 3) in the leſt upper lobe with histopathological description of undifferentiated carcinoma with spindle cells, nuclear pleomorphism, atypical mitosis. Immunohistochemical panel showed positive for AE1-AE3 and negative for the other markers (actin, desmin, S-100, TTF-1, bcl-2, CD45, CD34, CK7, estrogen and progesterone receptor, CD99). Completing the diagnosis of intimal sarcoma of the pulmonary artery mimicking pulmonary metastasis and TEP. Before the results of histopathology and immunohistochemistry, the hypothesis was lung cancer as a risk factor for pulmonary thromboembolism. Patient had significant worsening of dyspnea and underwent radiation therapy in an attempt to reduce the injury causing bronchial stenosis. Patient without conditions at the time of initiation of chemotherapy. Died due to respiratory failure and Abstract e intimal sarcoma of the pulmonary artery (SIAP) is a rare tumor of mesenchymal origin that primarily affects the large glass. e first report of the disease has been described in autopsy performed by Mandelstamm in 1923. On displays are oſten nonspecific signs and symptoms, the materials SIAP is commonly diagnosed as TEP, but other diagnoses are recognized as arteritis and pulmonary neoplasia pulmonar. e disease has a poor prognosis even aſter the intervention surgery, still considered the treatment of choice of treatment, and a few months to years. Raul Fava Alencar 1 , Filadélfia Passos Rodrigues 1 , José Aurillo Rocha 2 *, Fábio Rocha Fernandes Távora 3 , Victor S.M.de A. Meireles 4 and Paulo Henrique da Silva Leao 4 1 Department of Pulmonology, Messejana Hospital, Brazil 2 Department of Oncology, Clinical Pharmacology - Federal University of Ceara, Brazil 3 Department of Pathology, Messejana Hospital, Brazil 4 Messejana Hospital, Brazil