STUDY PROTOCOL Team based collaborative care model, facilitated by a mHealth enabled and trained nurse, for management of heart failure in India (TIME-HF): design and rationale of a parallel group, open label, multi-centric cluster randomized controlled trial [version 1; peer review: awaiting peer review] Panniyammakal Jeemon 1 , Charantharalyil Gopalan Bahuleyan 2 , Devaraju Chandgalu Javaregowda 3 , Eapen Punnoose 4 , Gopalan Rajendiran 5 , Govindan Unni 6 , Jabir Abdullakutty 7 , Jayakumar Balakrishnan 8 , Johny Joseph 9 , Justin Paul Gnanaraj 10 , Madhu Sreedharan 11 , Meera R Pillai 12 , Neenumol KR 1 , Paul Thomas 13 , Placid Sebastian 14 , Rachel Daniel 15 , Rajeev Edakutty 16 , Sajan Ahmad 17 , Shafeeq Mattummal 18 , Sunu C Thomas 1 , Stigi Joseph 19 , Sunil Pisharody 20 , Susanna Chacko 1 , N Syam 21 , Tiny Nair 22 , Veena Nanjappa 3 , Vijayan Ganesan 14 , Vijo George 13 , Sanjay Ganapathi 1 , Sivadasanpillai Harikrishnan 1 1 KIMS Hospital, Thiruvananthapuram, Kerala, India 2 General Hospital, Ernakulam, Kerala, India 3 Aster MIMS, Kannur, Kerala, India 4 NS Memorial Institute of Medical Sciences, Kollam, Kerala, India 5 District Cooperative Hospital, Calicut, Kerala, India 6 St Gregorios Memorial Mission Hospital, Parumala, Kerala, India 7 Aster MIMS, Calicut, Kerala, India 8 Little Flower Hospital and Research Centre, Angamaly, Ernakulam, Kerala, India 9 EMS Memorial Cooperative Hospital and Research Centre Ltd, Malappuram, Kerala, India 10 Government District Hospital, Kollam, Kerala, India 11 PRS Hospital, Thiruvananthapuram, Kerala, India 12 Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, 695011, India 13 Ananthapuri Hospitals and Research Institute, Thiruvananthapuram, Kerala, India 14 Sri Jayadeva Institute of Cardiovascular Science and Research, Mysore, Karnataka, India 15 Malankara Orthodox Syrian Church Medical College, Kolenchery, Kerala, India 16 PSG Institute of Medical Sciences, Coimbatore, Tamilnadu, India 17 Jubilee Mission medical College and Research Institute, Thrissur, Kerala, India 18 Lisie Hospital, Ernakulam, Kerala, India 19 Thangam Hospital of PMRC, Palakkad, Kerala, India 20 Caritas Hospital, Kottayam, Kerala, India 21 Rajiv Gandhi Government General Hospital, Madras Medical College, Chennai, Tamilnadu, India 22 NIMS Heart Foundation, NIMS Medicity, Thiruvananthapuram, Kerala, India First published: 03 May 2023, 8:197 Page 1 of 14 Wellcome Open Research 2023, 8:197 Last updated: 03 MAY 2023