INTRODUCTION Practice of intubation though born long ago, started gaining popularity and with it came the need for muscle relaxation.Today the prime concern and duty of the attending anaesthesiologist is protection of the airway, thus making tracheal intubation most essential procedure. To Prevent the hazard of intubation muscle relaxant play a decision role in facilitating a smooth intubation rst muscle relaxants curare in (1596).1949 Suxamethonium a depolarising neuromuscular blocking agent of rapid onset and brief duration of action.The next step was the search for a non depolariser with a quick onset of action. Patients requiring emergent endotracheal intubation often require a rapid sequence induction intubation (RSI) technique to protect against gastric aspiration, to facilitate intubation, or to protect against increased intracranial pressure. Succinylcholine is the most common muscle relaxant used because it has a fast onset and a short duration. Unfortunately it can have serious side effects as a result of it's membrane depolarizing effect and release of potassium. Rocuronium has been suggested to create intubating conditions similar to succinylcholine. Rocuronium bromide originally product org 9426, has a rapid onset time, intermediate duration of action, rapid recovery, no cumulation even on repeated administration cordiovascular stability, virtually no histamine release any other side effect.[1] MATERIAL & METHODS “The proposed study entitled “Comparison between Rocuronium Bromide & Succinylcholine Chloride in intubating conditions” was carried out in Department of Anaesthesiology, Gandhi Medical College & Hamidia Hospital, Bhopal (M.P.). 50 patients of either sex, aged between 18-60 yrs of ASA grade I/II, scheduled to undergo various surgical procedures were chosen as subjects of this study with informed consent. The sample size was calculated with the help of statistics on basis of study carried out. aOnset time (Apnea time), intubating condition, duration of action, haemodynamic changes at each point and adverse effect. Patients with potential airway problem, hepatic and renal dysfunction those receiving medication which can interfere with neuromascular function and haemodynamic like beta block, anticoagulent were excluded from study. Grouping was done into two lots of 25 each and randomly allocated Group I — Rocuronium bromide 0.6 mg/kg. Group II — Succinylcholine 1.5 mg/kg. Onset Time : The time between the end of injection of the muscle relaxant and onset of apnea time was noted intubation attempt was made after 60 secs. Intubating Conditions : The intubating conditions were evaluated and scoring was done according to vocal cord relaxation proposed by Cooper et al.[2] SCORING OF INTUBATING CONDITION Total Score 8 – 9 Excellent, 6-7 Good, 3-5 Fair, 0-2 Poor The Parameters recorded were heart rate, systolic blood pressure and diastolic blood pressure. These were measured pre operative for baseline value subsequently after induction, after intubation, 2 & 5 minutes thereafter. Adverse effect were observed during intubation and thereafter. OBSERVATIONS Table 1 : Incidence of grade of intubating condition Table shows that both rocuronium as well as succinylcholine provide excellent intubating conditionswith scores between 8-9 COMPARISON BETWEEN ROCURONIUM BROMIDE & SUCCHINYLCHOLINE IN INTUBATING CONDITION Original Research Paper Dr. Sukriti Atram Associate Professor. Department of Anaesthesiology J.J.Hospital Grants Medical College Mumbai X 37 GJRA - GLOBAL JOURNAL FOR RESEARCH ANALYSIS IF : 4.547 | IC Value 80.26 Volume : 3 | Issue : 11 | November 2014 • ISSN No 2277 - 8179 VOLUME-6, ISSUE-8, AUGUST-2017 • ISSN No 2277 - 8160 Aims and Objectives: To evaluate the quality of intubation of conditions.To evaluate the onset and duration of action . To evaluate heamodynamic changes and to assess the side effects and complication, if any of intubating doses Material & methods: The present study was carried out on fifty patients who were randomly allocated into two groups. Group I Those receiving Rocuronium bromide for intubation, in a dose of 0.6 mg/kg. Group II Those receiving Succinylcholine for intubation, in a dose of 1.5 mg/kg. Results : Intubation time did not differ between suxamethonium (9.8±2.2 s) (mean±SD) and rocuronium (10.5±2.9 s), respectively. Intubating conditions were clinically acceptable (good or excellent) in all patients given suxamethonium and in 96% of the patients given rocuronium. However, the condition of the vocal cords was better (P<0.05) and diaphragmatic response to intubation was less pronounced with suxamethonium (P<0.05). Changes in heart rate and arterial blood pressure were similar in both groups. (P<0.05) Conclusion :Rocuronium bromide at a dose of 0.6 mg/kg provides intubating conditions similar to succinylcholine 1.5 mg/kg at 1 minute. Therefore rocuronium is a suitable alternative to suxamethonium for intubation in elective, otherwise healthy patients with less side effects. KEYWORDS : ABSTRACT Anaesthesiology Dr Urmila Kesari Associatet Professor Department of Anaesthesiology, Gandhi Medical College & Hamidia Hospital, Bhopal . Corresponding author Scoring Jaw relaxation Vocal Cards Response to Intubation 0 Poor Closed Severe coughing or bucking 1 Minimal Closed Mild coughing 2 Moderate Moving Slight diaphragmative 3 Good Open None Grade Score Group I (Rocuronium bromide) Group II (Succinylcholine) No. of Patients % No. of Patients % Excellent 8-9 25 100 25 100 Good 6-7 - - - - Fair 3-5 - - - - Poor 0-2 - - - -