_____________________________________________________________________________________________________ *Corresponding author: E-mail: kaumi_alkali@yahoo.com; Asian Plant Res. J., vol. 12, no. 3, pp. 27-35, 2024 Asian Plant Research Journal Volume 12, Issue 3, Page 27-35, 2024; Article no.APRJ.115068 ISSN: 2581-9992 Qualitative and Quantitative Phytochemicals Screening of Aqueous, Methanol and Hexane Leaves Extracts of Senna Occidentalis Alkali K. a* , Dikwa K. B. b , G.A. Ajibade c , Y Magaji c and Abdulhamid M.B c a Department of G.S.T and Remedial, Mohammed Goni College of Legal and Islamic Studies, Nigeria. b Department of Biological Science, Nigerian Defence Academy, Kaduna, Nigeria. c Department of Medical Laboratory, University of Maidugur, Nigeria. Authors’ contributions This work was carried out in collaboration among all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/APRJ/2024/v12i3250 Open Peer Review History: This journal follows the Advanced Open Peer Review policy. Identity of the Reviewers, Editor(s) and additional Reviewers, peer review comments, different versions of the manuscript, comments of the editors, etc are available here: https://www.sdiarticle5.com/review-history/115068 Received: 03/02/2024 Accepted: 07/04/2024 Published: 13/04/2024 ABSTRACT The Senna occidentalis tree is an incredible plant with incredible antimicrobial, antifungal and antimalarial activities used traditionally. The study was carried out to determine the phytochemical content responsible for these activities Fresh leaves were collected, aqueous, methanolic and hexane extracts of leaves were prepared, and the extracts were screened for phytochemical constituents using standard methods. Results of the phytochemical screening of all the crude extracts revealed the presence of saponins, tannins, steroids, phenol, alkaloid and flavonoid. In aqeuose extract, flavonoid show higher content of 2,47%, followed by tepernoid with 2.27%, methanol with higher content of tepernoid with 2.60%, and hexane with the highest in tepernoid Original Research Article