Accepted Manuscript Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort Carlos H. Martinez, MD, MPH, Sara X. Li, MD, Andrew J. Hirzel, BS, Valerie R. Stolberg, MPH, Neil E. Alexis, PhD, R. Graham Barr, MD, PhD, Eugene R. Bleecker, MD, Elizabeth E. Carretta, MPH, Stephanie A. Christenson, MD, Christopher B. Cooper, MD, David J. Couper, PhD, Claire M. Doerschuk, MD, MeiLan K. Han, MD, MS, Nadia N. Hansel, MD, MPH, Annette T. Hastie, PhD, Eric A. Hoffman, PhD, Robert J. Kaner, MD, Fernando J. Martinez, MD, MS, Deborah A. Meyers, PhD, Wanda K. O’Neal, PhD, Robert Paine, III, MD, Nirupama Putcha, MD, MHS, Stephen I. Rennard, MD, Prescott G. Woodruff, MD, MPH, Michelle Zeidler, MD, Jeffrey L. Curtis, MD, Christine M. Freeman, PhD PII: S0091-6749(17)31432-X DOI: 10.1016/j.jaci.2017.07.039 Reference: YMAI 12999 To appear in: Journal of Allergy and Clinical Immunology Received Date: 19 December 2016 Revised Date: 6 July 2017 Accepted Date: 12 July 2017 Please cite this article as: Martinez CH, Li SX, Hirzel AJ, Stolberg VR, Alexis NE, Barr RG, Bleecker ER, Carretta EE, Christenson SA, Cooper CB, Couper DJ, Doerschuk CM, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kaner RJ, Martinez FJ, Meyers DA, O’Neal WK, Paine III R, Putcha N, Rennard SI, Woodruff PG, Zeidler M, Curtis JL, Freeman CM, for the SPIROMICS Investigators, Alveolar eosinophilia in current smokers with chronic obstructive pulmonary disease in the SPIROMICS cohort, Journal of Allergy and Clinical Immunology (2017), doi: 10.1016/j.jaci.2017.07.039. This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.