ABSTRACT This paper explores the transformative role of Artificial Intelligence (AI) in business decision- making within Nigerian organizations. As AI technologies become increasingly integral to global business environments, their adoption in Nigeria is steadily growing. This study examines how AI is supporting strategic decisions, improving operational efficiency, and driving innovation in sectors including finance, healthcare, retail, and manufacturing. Data was gathered through qualitative methods involving 80 questionnaires and semi-structured interviews with business executives and IT managers across Lagos, Abuja, Port Harcourt, and Kano. The findings indicate a positive correlation between AI integration and enhanced decision-making capabilities, operational optimization, and innovative product development. However, challenges such as inadequate infrastructure, limited AI literacy, and ethical concerns hinder widespread adoption. The study concludes with recommendations for policymakers and business leaders to foster an enabling environment for AI. Keywords: Artificial Intelligence, Business Decision-Making, Operational Efficiency, Innovation, Nigerian Organizations, Technology Adoption 1. INTRODUCTION Artificial Intelligence (AI) has emerged as one of the most significant technological advancements of the 21st century, profoundly transforming the global business landscape. It encompasses a wide range of technologies, including machine learning, natural language processing, robotics, and predictive analytics, all aimed at enabling machines to perform tasks that typically require human intelligence. In the Nigerian context, the potential of AI is increasingly being recognized as a catalyst for sustainable economic growth, particularly in enhancing business decision-making, operational efficiency, and innovation. As organizations navigate a rapidly evolving market environment characterized by volatility, uncertainty, complexity, and ambiguity (VUCA), decision-makers are under constant pressure to make faster and more informed choices. AI offers a solution by providing real-time insights, automating repetitive tasks, and uncovering patterns in massive datasets that would otherwise remain hidden. In Nigeria, the growing digital economy, coupled with increased investments in tech startups and digital infrastructure, presents a fertile ground for the adoption of AI-driven solutions. 1 The Impact of Artificial Intelligence on Business Decision-Making A Study of Nigerian Organizations Andoon Nancy Tali (DBA/2325/0001377) Department of Business Administration The University Of America, Willemstad, Curacao