A Multi-Trait Multi-Method Examination of Psychometric Instrument Performance in Autism Spectrum Disorder Michael A. Levine, M.S. a , Huan Chen, B.S. b , Ericka L. Wodka, Ph.D. c , Brian S. Caffo, Ph.D. b , Joshua B. Ewen, M.D. a,d,e a Neurology and Developmental Medicine, Kennedy Krieger Institute, Baltimore, MD, USA b Department of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA c Center for Autism and Related Disorders, Kennedy Krieger Institute, Baltimore, MD, USA d Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA e Psychological and Brain Sciences, Johns Hopkins University, Baltimore, MD, USA Corresponding Author: Joshua B. Ewen, MD Address: Kennedy Krieger Institute, 707 North Broadway, Baltimore, MD 21205, USA Email: ewen@kennedykrieger.org Phone: 443-923-7990 Acknowledgements: The authors wish to acknowledge the Center for Neurodevelopmental and Imaging Research for sharing data in support of this work. Funding for this work came from the NIH grant R01MH113652 to JBE and P50HD103538. Funding sources were not involved in the analysis or interpretation of data, writing of the report, or the decision to submit for publication.