International Journal of Research in Medical Sciences | December 2016 | Vol 4 | Issue 12 Page 5334 International Journal of Research in Medical Sciences Patodi V et al. Int J Res Med Sci. 2016 Dec;4(12):5334-5340 www.msjonline.org pISSN 2320-6071 | eISSN 2320-6012 Original Research Article A comparative study between ProSeal laryngeal mask airway and endotracheal tube for ease of insertion and haemodynamic changes in patients undergoing laparoscopic cholecystectomy under general anaesthesia Veena Patodi*, Maina Singh, Surendra K. Sethi, Vini N. Depal, Neena Jain, Vijay Kumar INTRODUCTION Airway management is very crucial for an anaesthesiologist despite significant advances in the anaesthetic practice from time to time. The cuffed endotracheal tube was considered as the gold standard for providing an adequate and effective glottic seal for positive pressure ventilation, prevents gastric insufflation and aspiration particularly for laparoscopic procedures under general anaesthesia where pneumoperitoneum decreases the pulmonary compliance, reduces functional residual capacity and increases airway pressures. However, the use of endotracheal tube may be associated with various problems like haemodynamic pressor response, dental trauma, cough and sore throat. So this warrants searching for a newer alternative device which ABSTRACT Background: The endotracheal tube is considered a gold standard for providing a safe and effective glottic seal, especially for laparoscopic procedures under general anaesthesia. However, haemodynamic pressor responses associated with its use might be detrimental. The ProSeal LMA minimizes this response without compromising the airway with lesser incidence of complications. The aim of this study was to compare ProSeal LMA and Endotracheal tube with respect to intra-operative haemodynamic responses and ease of insertion of device and nasogastric tube in patients undergoing laparoscopic surgeries under general anaesthesia. Methods: This prospective randomized study was conducted on sixty patients, aged 20-60 years; of ASA grade 1 or 2, 30 in each group, posted for laparoscopic cholecystectomy under general anaesthesia. After induction with propofol and neuromuscular blockade with rocuronium, PLMA or ETT was inserted. The haemodynamic responses and insertion time of device and nasogastric tube were noted. Postoperative complications, if any were also noted. Results: The mean time of insertion of PLMA was 37.40±16.09 seconds and for intubation (ETT) was 31.17±20.89 seconds which was statistically not significant (P >0.05). The mean time of insertion of nasogastric tube was 18.84±6.84 seconds in PLMA group and 73.00±71.06 seconds in the ETT group which was highly significant, (P <0.001). There was a statistically significant increase in the heart rate(HR),systolic blood pressure (SBP),diastolic blood pressure (DBP) and mean arterial pressure (MAP) at intubation that persisted till 5 minutes of intubation and also at the time of extubation in ETT group, (P <0.05). However, the haemodynamic parameters remained comparable to baseline values, after insertion of ProSeal and at its removal in PLMA group (P>0.05). Conclusions: ProSeal LMA proved to be a suitable alternative to endotracheal tube for airway management with stable haemodynamics in patients undergoing laparoscopic cholecystectomy under general anaesthesia. Keywords: Ease of insertion, Endotracheal tube, Haemodynamics, Laparoscopic surgeries, ProSeal LMA Department of Anaesthesiology, JLN Medical College and Hospital, Ajmer, Rajasthan, India Received: 04 October 2016 Accepted: 04 November 2016 *Correspondence: Dr. Veena Patodi, E-mail: veenapatodi@gmail.com Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20164205