Outcomes of older adults aged 90 and over with cutaneous malignancies after electrochemotherapy with bleomycin: A matched cohort analysis from the InspECT registry Gregor Sersa a, b , Matteo Mascherini c , Claudia Di Prata d , Joy Odili e , Francesca de Terlizzi f , Gordon A.G. McKenzie g , A. James P. Clover h , Giulia Bertino i , Romina Spina j , Ales Groselj k, l , Rocco Cappellesso m , Julie Gehl n, o , Brian Bisase p , Pietro Curatolo q , Erika Kis r , Valbona Lico s , Tobian Muir t , Antonio Orlando u , Pietro Quaglino v , Paolo Matteucci w , Sara Valpione x , Luca G. Campana y, z, * a Institute of Oncology Ljubljana, Department of Experimental Oncology, Zaloska 2, SI-1000, Ljubljana, Slovenia b University of Ljubljana, Faculty of Health Sciences, Zdravstvena Pot 5, SI-1000, Ljubljana, Slovenia c Clinica Chirurgica-1, Ospedale Policlinico San Martino, University of Genova, Italy d University of Padua School of Surgery, Padua, Italy e Department of Plastic Surgery, St George’s Hospital, London, United Kingdom f Scientific & Medical Department, IGEA S.p.A, Via Parmenide 10/A, 41012, Carpi, Mo, Italy g Wolfson Palliative Care Research Centre, Hull York Medical School, Allam Medical Building, University of Hull, Hull HU6 7RX, United Kingdom h Department of Plastic Surgery, Cork University Hospital and Cancer Research@UCC, University College Cork, Cork, Ireland i Department of Otorhinolaryngology, University of Pavia, IRCCS Policlinico San Matteo Foundation, 27100, Pavia, Italy j Veneto Institute of Oncology IOV-IRCCS, Padua, Italy k Department of Otorhinolaryngology and Cervicofacial Surgery, University Medical Centre Ljubljana, Zaloska 2, SI-1000, Ljubljana, Slovenia l University of Ljubljana, Faculty of Medicine, Vrazov trg 2, SI-1000, Ljubljana, Slovenia m Pathological Anatomy Unit, Padua University Hospital, Padua, 35121, Italy n Center for Experimental Drug and Gene Electrotransfer (C*EDGE), Department of Clinical Oncology and Palliative Care, Zealand University Hospital, Køge, Denmark o Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark p Clinic for Head & Neck Cancer, Queen Victoria Hospital NHS Foundation Trust, West Sussex, United Kingdom q Department of Internal Medicine and Medical Specialties - Division of Dermatology, University “La Sapienza”, Rome, Italy r Department of Dermatology and Allergology, University of Szeged, Hungary s Chirurgia Generale ULSS 3, erenissima, Mirano, Italy t James Cook University Hospital, Middlesbrough, United Kingdom u Department of Plastic and Reconstructive Surgery, Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom v Dermatologic Clinic, Department of Medical Sciences, University of Turin Medical School, Turin, Italy w Hull University Teaching Hospitals NHS Trust, Hull, United Kingdom x Cancer Research UK, The University of Manchester, The Christie NHS Foundation Trust, Manchester, United Kingdom y Department of Surgical Oncological and Gastroenterological Sciences (DISCOG), University of Padua, Padua, Italy z The Christie NHS Foundation Trust, Manchester, United Kingdom article info Article history: Received 9 September 2020 Received in revised form 9 October 2020 Accepted 30 October 2020 Available online xxx abstract Background: With extending life expectancy, more people are diagnosed with cutaneous malignancies at advanced ages and are offered nonsurgical treatment. We assessed outcomes of the oldest-old adults after electrochemotherapy (ECT). Methods: The International Network for Sharing Practices of ECT (InspECT) registry was queried for adults aged 90 years (ys) with skin cancers/cutaneous metastases of any histotype who underwent * Corresponding author. Department of Surgical Oncological and Gastroenterological Sciences (DISCOG), University of Padua, Via Giustiniani 2, Padua, Italy. E-mail addresses: gsersa@onko-i.si (G. Sersa), mascherinimatteo@gmail.com (M. Mascherini), claudia.diprata.md@gmail.com (C. Di Prata), joy.odili@virginmedia.com (J. Odili), f.deterlizzi@igeamedical.com (F. de Terlizzi), Gordon.McKenzie@hey.nhs.uk (G.A.G. McKenzie), j.clover@ucc.ie (A.J.P. Clover), giulia.bertino68@gmail.com (G. Bertino), romina.spina@iov.veneto.it (R. Spina), ales.groselj@kclj.si (A. Groselj), rocco.cappellesso@gmail.com (R. Cappellesso), kgeh@regionsjaelland.dk (J. Gehl), brian. bisase@nhs.net (B. Bisase), pietro.curatolo@uniroma1.it (P. Curatolo), ksgbrll@gmail.com (E. Kis), valbona.lico@aulss3.veneto.it (V. Lico), tobian.muir@nhs.net (T. Muir), antonio.orlando@nbt.nhs.uk (A. Orlando), pietro.quaglino@unito.it (P. Quaglino), paolo.matteucci@hey.nhs.uk (P. Matteucci), sara.valpione@cruk.manchester.ac.uk (S. Valpione), luca.campana@nhs.net (L.G. Campana). Contents lists available at ScienceDirect European Journal of Surgical Oncology journal homepage: www.ejso.com https://doi.org/10.1016/j.ejso.2020.10.037 0748-7983/© 2020 Elsevier Ltd, BASO ~ The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved. European Journal of Surgical Oncology xxx (xxxx) xxx Please cite this article as: G. Sersa, M. Mascherini, C. Di Prata et al., Outcomes of older adults aged 90 and over with cutaneous malignancies after electrochemotherapy with bleomycin: A matched cohort analysis from the InspECT registry, European Journal of Surgical Oncology, https:// doi.org/10.1016/j.ejso.2020.10.037