Addis Ababa University School of Graduate Studies Biotechnology Program Production, characterization, and potential application of a keratinolytic alkaline protease produced by alkaliphilic Vibrio sp. A Thesis Submitted to the School of Graduate Studies Addis Ababa University In Partial Fulfillment of the Requirement for the Degree of Master of Science in Biotechnology By Muhammed Seid Advisor: Amare Gessesse (PhD) May 2011 Addis Ababa