11 11 TSH DAN fT4 DENGAN INDEKS MASSA TUBUH (IMT) PADA PASIEN DEWASA: STUDI CROSS-SECTIONAL DI KLINIK LITBANGKES MAGELANG TSH and fT4 with Body Mass Index (BMI) in Adults Patients: A Cross-sectional Study in The Litbangkes Clinic, Magelang Cicik Harfana 1 , Ali Rosidi 2* ,Yuliana Noor Setiawati Ulvie 2 , Ria Purnawian Sulistiani 2 1 Balai Penelitian dan Pengembangan Kesehatan Magelang Kapling Jayan, Borobudur, Magelang, Jawa Tengah, Indonesia 2 Program Studi Gizi Fakultas Ilmu Keperawatan dan Kesehatan Universitas Muhammadiyah Semarang Jalan Kedungmundu Raya Nomor 18, Semarang, Jawa Tengah, Indonesia *e-mail: alirhesa@yahoo.co.id Submitted: May 7 th , 2021, revised: August 9 th , 2021, approved: October 17 th , 2021 ABSTRACT Background. Thyroid dysfunction occurs when the thyroid gland’s is impaired, as evidenced by elevated or decreased levels of thyroid-stimulating hormone (TSH) and free thyroxine (fT4). Thyroid hormone levels fluctuate, causing changes in the basal metabolic rate (BMR), affecting energy balance and body weight. Objective. This study aimed to analyze the relationship between TSH and fT4 and body mass index (BMI) in new adult patients at the Litbangkes Clinic in Magelang. Method. This research used a cross-sectional method and used secondary data from the patient’s medical records. The research sample was 173 adult men and women (>17 years) who visited the Litbangkes Clinic in 2019. Thyroid-stimulating hormone (TSH), fT4, and BMI were the research variables. The Spearman Rank Correlation statistical test is used to test hypotheses. Result. The average TSH level of the respondents was normal, namely 0.91±2.17 µIU/mL, while the average respondent’s fT4 level was above normal, at 3.20±5.83 ng/dL. The majority of the participants (55.5%) had a normal BMI, with a mean of 23.74±4.57. The Spearman Rank Correlation test shows that there is a significant relationship between TSH and BMI (p=0.003) with a positive correlation (r=0.228) and there is a significant relationship between fT4 and BMI (p=0.000) with a negative correlation (r=-0.323). Conclusion. There is a link between TSH and fT4 levels with the BMI of the patient. The higher the TSH level, the higher the BMI value of the patient, and vice versa; the higher the fT4 level, the lower the BMI value of the patient, and vice versa. Keywords: BMI, fT4, thyroid, TSH ABSTRAK Latar Belakang Disfungsi tiroid terjadi jika fungsi kelenjar tiroid terganggu, ditandai dengan kadar Thyroid Stimulating Hormone (TSH) dan free Thyroxine (fT4) yang lebih tinggi atau lebih rendah dari normal. Perubahan kadar hormon tiroid menyebabkan perubahan basal metabolic rate (BMR) yang menyebabkan perubahan keseimbangan energi dan berat badan. Tujuan. Penelitian bertujuan untuk menganalisis hubungan TSH dan fT4 dengan indeks massa tubuh (IMT) pada pasien dewasa baru di Klinik Litbangkes Magelang. Metode. Penelitian ini dilakukan dengan menggunakan metode cross-sectional dan menggunakan data sekunder dari rekam medis pasien. Sampel penelitian adalah pria dan wanita dewasa (>17 tahun) yang pertama kali mengunjungi Klinik Litbangkes Magelang pada tahun 2019 sebanyak 173 orang. Variabel penelitian adalah TSH, fT4, dan IMT. Pengujian hipotesis dengan uji statistik Korelasi Rank Spearman. Hasil. Rata-rata kadar TSH responden adalah normal yaitu 0,91±2,17 µIU/mL, sedangkan rata-rata kadar fT4 responden di atas normal yaitu 3,20±5,83 ng/dL. Sebagian besar subjek memiliki IMT normal (55,5%) dengan rata-rata 23,74±4,57. Uji Korelasi Rank Spearman https://doi.org/10.22435/mgmi.v13i1.4841;Copyright © 2021 MGMI