International Journal of Otorhinolaryngology and Head and Neck Surgery | September-October 2019 | Vol 5 | Issue 5 Page 1
International Journal of Otorhinolaryngology and Head and Neck Surgery
Manoj KL et al. Int J Otorhinolaryngol Head Neck Surg. 2019 Sep;5(5):xxx-xxx
http://www.ijorl.com
pISSN 2454-5929 | eISSN 2454-5937
Original Research Article
Prevalence of laryngopharyngeal reflux in adult population using
24 hours ambulatory dual probe pH monitoring
Manoj Kumar L., Anand K. H.*, Raadhika Shree N.
INTRODUCTION
The reflux of gastric contents is a major concern
involving the pathology of upper aerodigestive tract.
Small amount of the refluxate reach the upper aero-
digestive tract while upright during daytime causing
damage to the local tissue producing localized
symptoms.
1
According to El Serag, the prevalence of
reflux disease has increased by 4% every year since
1976.
2
Reflux is known to have been associated
subglottic stenosis, laryngospasm, bronchiectasis,
obstructive sleep apnoea and even rhinitis or chronic
sinusitis.
3
We conducted this study as laryngpharyngeal reflux is
growing problem in adult population due to lifestyle
changes.
METHODS
It is a prospective study conducted in the department of
otorhinolaryngology at Saveetha Medical College and
Hospital from April 2017 to April 2018. Adult patients
above 18 years of age were included in to the study.
Patients below 18 years of age, critically ill patients and
those taking anti reflux medications for the past 1month
were excluded from the study. Patients included in to the
study were now evaluated using reflux symptom index to
assess laryngopharyngeal reflux in the same. Reflux
symptom index if greater than 13 was suggestive of
laryngopharyngeal reflux according to Belafsky et al and
those patients were counselled to do ambulatory 24 hours
dual probe pH monitoring.
4
Informed consent was
obtained. Patient was prepped with 4% xylocaine
intranasally, dual probes 10 cms apart was used. The
ABSTRACT
Background: Laryngopharyngeal reflux disease is an under diagnosed condition due to unavailability of the
diagnostic tool that is dual probe pH monitoring and is on the rise in adult population according to El Serag by 4%
every year since 1976.
Methods: Adult patients coming to the outpatient department between April 2017 to April 2018 were evaluated using
reflux symptom index score (RSI). Score greater than 13 were suggestive of laryngopharyngeal reflux and patients
underwent 24 hours ambulatory dual probe pH monitoring. 7 or more reflux events in study period were diagnostic of
laryngopharygeal reflux.
Results: 3000 adult patients were screened for RSI and 1756 (58.3%) had scored greater than 13. Among these
patients 893 patients had 7 or more reflux events in pH monitoring. We found a prevalence of 29.76% in our study
population.
Conclusions: Prevalence laryngopharyngeal reflux disease needs to be assessed periodically at regular intervals to
create more awareness of the disease and patient education thus preventing from causing chronic illnesses.
Keywords: Laryngopharyngeal reflux, pH monitoring, Dual probe, Alkaline reflux, Reflux symptom index
Department of Otorhinolaryngology, Saveetha Medical College, Chennai, Tamil Nadu, India
Received: 15 July 2019
Accepted: 30 July 2019
*Correspondence:
Dr. Anand K. H.,
E-mail: dr.manojkumar247@gmail.com
Copyright: © the author(s), publisher and licensee Medip Academy. This is an open-access article distributed under
the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial
use, distribution, and reproduction in any medium, provided the original work is properly cited.
DOI: http://dx.doi.org/10.18203/issn.2454-5929.ijohns20193606