_____________________________________________________________________________________________________ *Corresponding author: E-mail: drozlemg81@hotmail.com; British Journal of Pharmaceutical Research 13(5): 1-8, 2016, Article no.BJPR.28762 ISSN: 2231-2919, NLM ID: 101631759 SCIENCEDOMAIN international www.sciencedomain.org Depression, Anxiety and Quality of Life among Chronic Low Back-leg Pain Patients with or without Neuropathic Pain Özlem Uzun 1* , Filiz Sivas Acar 1 , Bedriye Başkan 1 and Hatice Bodur 1 1 Ankara Numune Education and Research Hospital, Turkey. Authors’ contributions This work was carried out in collaboration between all authors. All authors read and approved the final manuscript. Article Information DOI: 10.9734/BJPR/2016/28762 Editor(s): (1) Cheng Wang, Division of Neurotoxicology, National Center for Toxicological Research (NCTR), Food and Drug Administration (FDA), USA. Reviewers: (1) Valery Piacherski, Mogilev Regional Hospital, Mogilev, Belarus. (2) Yildiz Degirmenci, Duzce University School of Medicine, Turkey. Complete Peer review History: http://www.sciencedomain.org/review-history/16719 Received 3 rd August 2016 Accepted 13 th October 2016 Published 28 th October 2016 ABSTRACT Aims: To investigate depression, anxiety and quality of life among chronic low back-leg pain patients with or without neuropathic pain. Place and Duration of Study: Ankara Numune Education and Research Hospital Department of Physical Medicine and Rehabilitation Polyclinic, between October 2012 and June 2013. Methodology: One hundred and one patients with chronic low back and leg pain were enrolled in the study. This study is a cross-sectional study. The severity of low back and leg pain was evaluated by visual analogue scale (VAS). The DN4 (Douleur Neuropathique en 4 Questions) and LANSS (Leeds Assessment of Neuropathic Symptoms and Signs) scales were used in order to evaluate the neuropathic pain. Existence of depression was evaluated by the Hamilton Depression Rating Scale (HAM-D) and anxiety was assessed by Hamilton Anxiety Rating Scale (HAM-A). The quality of life was questioned by Short Form-36 (SF-36). Results: Neuropathic pain was detected in 65.3% by DN4 and 40.6% by LANSS among all patients. According to HAM-D results, 22.7% of the patients had depression and according to HAM-A results, 8.9% of the patients had anxiety. While frequency of depression was statistically Original Research Article