DOI: 10.18410/jebmh/2015/748 ORIGINAL ARTICLE J of Evidence Based Med & Hlthcare, pISSN- 2349-2562, eISSN- 2349-2570/ Vol. 2/Issue 35/Aug. 31, 2015 Page 5377 NIPPLE AREOLA COMPLEX INVOLVEMENT IN EARLY AND LATE CARCINOMA BREAST Firoz Chowdhury 1 , Jaydeep Mondal 2 , Joydip Paul 3 , Sejuti Sen Dutta 4 , Paromita Roy Chandra 5 , Monimala Saha 6 , Sandip Chattopadhyay 7 , Anjan Das 8 HOW TO CITE THIS ARTICLE: Firoz Chowdhury, Jaydeep Mondal, Joydip Paul, Sejuti Sen Dutta, Paromita Roy Chandra, Monimala Saha, Sandip Chattopadhyay, Anjan Das. “Nipple Areola Complex Involvement in Early and Late Carcinoma Breast”. Journal of Evidence based Medicine and Healthcare; Volume 2, Issue 35, August 31, 2015; Page: 5377-5382, DOI: 10.18410/jebmh/2015/748 ABSTRACT: BACKGROUND: The last several decades have witnessed significant advances in the surgical management of carcinoma breast. Many have embraced breast conservation as the procedure of choice in carefully selected patients. It provides excellent cosmetic results side by side being oncologically safe. Recent evidences have shown that involvement of nipple areola complex in breast cancer have been over estimated in the past based on older concept of occult tumor in the region of nipple and areola. Preservation of nipple and areola improves the quality of life and reduces the feeling of mutilation and thus is a logical step in conservative management of breast carcinoma. AIMS: (a) To investigate the actual involvement of nipple areola complex clinically and histopathologically. (b) To determine the associated risk factors like site, size, distance, grading and lymph node status. MATERIALS AND METHODS: This was a prospective study over a period of 2008 -2011 carried out at Department of General Surgery of a tertiary care centre. Total number of patients included in the study was 54. All patients included in the study had undergone mastectomy for carcinoma of breast (excluding those patients who had clinical involvement of nipple areola complex). RESULTS: Among the patients of the study group majority of breast cancer occurred in age group 41-60 years (42.6%) while incidence of nipple areola involvement was highest in age group 20-40 years. Majority of the patients detected with breast cancer were in stage II (44.4%) while incidence of nipple areola involvement was highest in stage IV in our study. Mean largest dimension of the tumor was between 2-5cms while nipple areola involvement was found to be highest when the tumor is >5cms in largest dimension. Among the cases mean nipple tumor margin distance was between 0-4cms while nipple areola involvement was found to be highest when the nipple tumor margin distance was < 2cms. CONCLUSION: It can be concluded that nipple areola complex sparing mastectomy is an attractive and safe procedure for early breast cancer KEYWORDS: Clinico-pathological study, Nipple areola complex (NAC), Carcinoma (CA) breast. INTRODUCTION: The management of breast carcinoma has been revolutionized over last few decades. The concern has shifted to proper management together with cosmetic appearance of the patient. Many have embraced breast conservation as the procedure of choice in carefully selected patients. It provides excellent cosmetic results side by side being oncologically safe. The involvement of nipple areola complex depends on several important factors; like -Tumor size, Tumor nipple distance, Histological type of tumor, Axillary lymph node status, Nuclear grading of tumor, Receptor status and Genetics.