Indo-Global Journal of Pharmaceutical Sciences, 2011, Vol 1., Issue 1: Page No. 25-32 25 Antioxidant Potential of Some Under-Utilized Fruits Dhan Prakash *a , Garima Upadhyay b , P Pushpangadan a a Amity Institute of Herbal Research & Studies, Amity University, UP, Sector-125, Noida-201303, G B Nagar, UP, India b Department of Pomology, College of Horticulture & Forestry, Central Agricultural University, Pasighat-791102, Arunachal Pradesh, India Received: 07 th Dec. 2010; Accepted: 09 th Jan 2011 Address for Correspondance: dprakash_in@yahoo.com Abstract— To identify their potential sources extracts of some fruits and their different parts were studied for total phenolic contents (TPC), antioxidant (AOA) and free radical scavenging activities (FRSA). Phenols have profound importance due to their biological and free radical scavenging activities. The amount of TPC varied from 10.5 to 343.2 mg/g and AOA from 20.3 to 96.7%. Fruits of Caesalpinia mexicana, Acacia auriculiformis, fruit pericarp fibres of Cocus nucifera, and fruits of Emblica officinalis were found to have high TPC (73.1-343.2 mg/g) and high AOA (68.5-96.7%). Promising fruits were studied for their FRSA and reducing power (RP) measured by DPPH assay where the fruits of Caesalpinia mexicana, fruit pericarp fibres of Cocus nucifera, fruits of Emblica officinalis showed very low IC 50 ranging from 0.009 to 0.016 mg/ml, EC 50 from 0.39 to 0.70 mg/mg DPPH and reasonably high values (142.1- 256.3) of anti radical power (ARP), indicating their strong FRSA and reducing power (RP) as evident by their low ASE/ml values (0.42- 1.08). They also showed better inhibition of lipid peroxidation measured by using ferric thiocyanate assay and by using egg yolk compared to reference standard, quercetin. The ferrous and ferric ion chelating capacity of the promising fruits and their underutilized parts in terms of IC 50 varied from 0.12 (Emblica officinalis, fruits) to 2.44 mg/ml (Mangifera indica, Seed kernel) and 0.22 (Caesalpinia mexicana, fruits) to 2.59 mg/ml (Litchi chinensis, fruit peel) respectively. Fruit of Acacia auriculiformis, Caesalpinia mexicana, Emblica officinalis, fruit pericarp fibres of Cocus nucifera, were also assayed for their specific phenolic composition through HPLC where the amount of caffeic acid varied from 48.5 to 2231 μg/g, chlorogenic acid 63.8 to 912.1 μg/g, ellagic acid 46.4 to 1429.1 μg/g, ferulic acid 36.7 to 762.9 μg/g, gallic acid 181.6 to 2831.6 μg/g, protocatechuic acid 41.7 to 322.8 μg/g, and quercetin 44.6 to 367.6 μg/g. © 2011 IGJPS. All rights reserved Keywords : Total Phenols, Antioxidant activity, Free Radical Scavenging Activity, Anti Radical Power, Reducing Power. INDO GLOBAL JOURNAL OF PHARMACEUTICAL SCIENCES