Retrospective Evaluation and Correction of Intensity Inhomogeneity Martin Styner 1 , Koen Van Leemput 2 1 : University of North Carolina, Department of Computer Science, Chapel Hill, USA 2 : HUS Helsinki Medical Imaging Center, Helsinki, Finland September 7, 2004 Contents 1 Introduction 2 2 Early Solutions 4 3 Combined Segmentation and Inhomogeneity Correction Methods 5 4 Correction Based on Evaluation of the Histogram 13 4.1 PABIC - Parametric Bias Correction ......................... 13 4.2 Information Minimization and N3 ........................... 15 5 Discussion and Conclusion 16 1