444
Unusual Course of Reaction of Buta-1,3-diene-
1,4-diylbis(triphenylphosphonium Chloride)
with Phenylhydrazine
M. Zh. Ovakimyan, M. L. Movsisyan, G. A. Gasparyan, and M. G. Indzhikyan
Institute of Organic Chemistry, National Academy of Sciences of Armenia,
ul. Z. Kanakertsy 167a, Yerevan, 375091 Armenia
e-mail: ioc_phos@mail.ru
Received July 20, 2010
LETTERS
TO THE EDITOR
ISSN 1070-3632, Russian Journal of General Chemistry, 2011, Vol. 81, No. 2, pp. 444–446. © Pleiades Publishing, Ltd., 2011.
Original Russian Text © M.Zh. Ovakimyan, M.L. Movsisyan, G.A. Gasparyan, M.G. Indzhikyan, 2011, published in Zhurnal Obshchei Khimii, 2011, Vol. 81,
No. 2, pp. 346–348.
Previously we have found that triphenyl- and tri-
butyl-2-phenylhydrazinoethylphosphonium salts when
heated in ethanol or DMF are dehydrated to form
phenylhydrazones of the corresponding phosphonium
acetic aldehydes in high yields [1]. The same reaction
occurred in the case of triphenyl- and tributyl-
phosphonium salts with 4-N-phenylhydrazino-3-chloro-
but-2-enyl group [2].
Based on the results of these studies we suggested
that this reaction had a cyclic nature including the shift
of a lone electron pair to the onium phosphorus atom
and the hydride ion expulsion from the neighboring
sp
3
-carbon atom [3].
We found that buta-1,3-diene-1,4-diylbis-
(triphenylphosphonium chloride) I at reflux with 2 mol
of phenylhydrazine in chloroform formed 2-phenyl-
hydrazonobutane-1,4-diylbis(triphosphonium chloride)
II in 85% yield. Yield of compound II decreased to
51% when the starting reagents were used in the
equimolar ratio. The reaction was accompanied in both
cases with the formation of phenylhydrazine hydro-
chloride in high amounts. The latter was established to
form by the reaction of phenylhydrazine with
chloroform. As expected, the reaction of salt I with
equimolr amount of phenylhydrazine in acetonitrile
affords compound II almost in the quantitative yield.
Probably the formation of salt II occurs through initial
addition of phenylhydrazine at one of multiple bonds
of salt I to give intermediate III followed by hydro-
genation of the multiple bond involving the transfer of
a hydride ion by the cyclic mechanism:
DOI: 10.1134/S1070363211020344
Cl
-
Ph
3
P
PPh
3
+
+
Cl
-
PhNHNH
2
Cl
-
Ph
3
P
PPh
3
+
+
Cl
-
H
N H
PhNH
Cl
-
Ph
3
P
PPh
3
+
+
Cl
-
II
NNHPh
I III
Cl
-
Ph
3
P
PPh
3
+
+
Cl
-
3 PhNHNH
2
IV
Ph
3
P
NNHPh
+
V
+ II + Ph
3
P=NHNHPh + Ph
3
PO
+
VI
Cl
-
Compound II was found to form also from 2-
butene-1,4-diylbis(triphenylphosphonium chloride) IV
via the reaction with threefold excess of phenyl-
hydrazine in chloroform, but its yield was 7% only. At
the same time among the reaction products were also
triphenyl(4-phenylhydrazonobut-2-enyl)phosphonium
chloride V (46%), triphenylphosphine oxide (34%),
and N-phenyltriphenylphosphine imine hydrochloride
VI (19%), identified by the
1
Н NMR and elemental
analysis data, and phenylhydrazine hydrochloride.