1063-7710/05/5104- $26.00 © 2005 Pleiades Publishing, Inc. 0376
Acoustical Physics, Vol. 51, No. 4, 2005, pp. 376–384. Translated from Akusticheskiœ Zhurnal, Vol. 51, No. 4, 2005, pp. 447–455.
Original Russian Text Copyright © 2005 by Anosov, Gavrilov.
An important characteristic of a human body is the
spatial distribution of the in-depth temperature. Tem-
perature monitoring is necessary for various therapeu-
tic procedures, such as, for example, hyperthermia in
oncology. In this procedure, it is important to heat a
tumor up to a certain optimal temperature, for example,
to 43–44°ë, and, then, to maintain the temperature for
several or several tens of minutes. Monitoring is effec-
tive if it is possible to measure the temperature at a
depth of 3–8 cm in a volume of about 1 cm
3
with an
accuracy of about 0.5 K. For such measurements it is
desirable to use nondestructive and noninvasive tech-
niques, for example, to receive the thermal acoustic
radiation from a biological object in the ultrasonic fre-
quency range.
In the previous publications [1, 2], the problem of
reconstructing the in-depth temperature of a biological
object was theoretically investigated and the recon-
struction parameters were evaluated. However, in solv-
ing this problem, the directivity patterns of receivers
were approximated by beams and the ultrasonic
absorption coefficient in a biological object was
assumed to be known, which is not always possible.
Experiments on the reconstruction (using the indicated
assumptions) of the in-depth temperature in glycerol
and in a human hand were carried out in [2]. The
authors of [3–5] theoretically and experimentally
reconstructed the position of a heat source within
model objects, in some cases, with the use of focused
receivers [4, 5]. However, the temperature parameters
of the distribution were not evaluated. The authors of
[2, 6–8] theoretically and experimentally investigated
the abilities of the correlation detection of thermal
acoustic radiation in determining the internal tempera-
ture of a biological object. In this case, the accuracy of
the reconstruction was not estimated.
The purpose of the present study is to theoretically
investigate the feasibility of the reconstruction of a two-
dimensional temperature distribution with the use of
linear phased arrays by taking into account the actual
directivity patterns of the arrays and by assuming that
data on the absorption coefficient are absent. We pro-
pose to determine the form of the temperature distribu-
tion in two mutually perpendicular directions from the
results of electronic scanning of a biological object by
two phased arrays and to reconstruct the absorption
coefficient in the medium from the difference between
the signals measured by these arrays. Then, using the
information on the form of the distribution and on the
absorption coefficient, we propose to calculate the
amplitude of the temperature peak and, thus, to com-
pletely reconstruct the temperature distribution.
Let us consider the measurement scheme (Fig. 1)
proposed for the solution of a two-dimensional prob-
lem. (1) A biological object is located within the right
angle formed by two rays, 0x and 0z. We assume that
ultrasonic absorption within the biological object is
constant and determined by the absorption coefficient
α
0
. The value of α depends on the frequency of the
received signal. We assume that the measurement of
thermal acoustic radiation is performed in soft tissue in
a frequency range of about 1 MHz and that the ampli-
tude absorption coefficient is α ≈ 0.1 cm
–1
[9]. We also
assume that the attenuation coefficient α is numerically
equal to α
0
, since the contribution of scattering to atten-
uation in soft tissues (usually no greater than 10–15%
Reconstruction of the In-Depth Temperature Distribution
for Biological Objects by Linear Phased Arrays
A. A. Anosov* and L. R. Gavrilov**
* ELDIS Research Center for Electronic Diagnostic Systems, Russian Academy of Sciences,
Starosadskiœ per. 8, Moscow, 101000 Russia
** Andreev Acoustics Institute, Russian Academy of Sciences,
ul. Shvernika 4, Moscow, 117036 Russia
e-mail: anosov@hotmail.ru
Received December 2, 2003
Abstract—The feasibility of the reconstruction of two-dimensional temperature distributions in biological
objects with the use of linear phased arrays is investigated theoretically with allowances made for the actual
array directivity patterns and without using the data on the absorption coefficient. The method provides an
opportunity to reconstruct the temperature distribution in the region under investigation with an accuracy of
about 0.5 K from the data of 1.5-min-long measurements when the temperature of the region of interest is
raised by 5–10 K. © 2005 Pleiades Publishing, Inc.