Alamat Korespondensi: Bagian Prostodonsia Fakultas Kedokteran Gigi Universitas Gadjah Mada Indonesian Journal of Dentistry 2008; 15 (3):187-191 Fakultas Kedokteran Gigi http//www.fkg.ui.edu Universitas Indonesia ISSN 1693-9697 PENGARUH EKSTRAK GRAPTOPHYLLUM PICTUM TERHADAP PERTUMBUHAN CANDIDA ALBICANS PADA PLAT GIGI TIRUAN RESIN AKRILIK Endang Wahyuningtyas Bagian Prostodonsia Fakultas Kedokteran Gigi Universitas Gadjah Mada Abstract Graptophyllum pictum (Daun ungu) is one of the traditional plants in Indonesia. Graptophyllum pictum composition is flavonoid, Flavonoid has an antimicrobial effect. The purpose of this study is to find the effect of Graptophyllum pictum extract prevent the growth of Candida albicans on acrylic resin denture plate. The research was done plaque smear which Candida albicans adhered at the patient denture, then it was cultured and Candida albicans growth was cultivated. The research was done by using 40 samples. The samples were heat cured acrylic resin discs with 10 mm diameter. The research was used dilution method. The samples were divided into four groups.. Each group had been given Graptophyllum pictum extract with 5%, 10%, 20% and 40% for 8 hours. The plates with Sabouraud agar were incubated at 37 o C for 24 hours and then Candida albicans were counted. The data were analyzed by the One way variant analysis and t-test. The result showed there were significant differences among the amount of Candida albicans which grew in different concentration of Graptophyllum pictum extract (p < 0.05). The conclusion was that Graptophyllum pictum extract had prevented the growth of Candida albicans on acrylic resin denture plate. Pendahuluan Resin akrilik merupakan bahan yang hingga saat ini masih digunakan di bidang Kedokteran Gigi. Lebih dari 95% plat gigi tiruan dibuat dari bahan resin akrilik. 1 Resin akrilik head cured memenuhi persyaratan sebagai bahan plat gigi tiruan karena tidak bersifat toksik, tidak mengiritasi jaringan, sifat fisik dan estetik baik, harga relatif murah, dapat direparasi, mudah cara manipulasi dan pembuatannya. 2 Endang Wahyuningtyas Key words: Graptophyllum pictum extract, Candida albicans, Acrylic resin denture plate.