1 ABSTRAC EFFECT OF THE USE OF SUPPLEMENTS PSIDII FOLIUM EXTRACT (PSIDIUM GUAJAVA LINN.) AND RED FERMENTED RICE (MONASCUS PURPUREUS) IN INCREASE OF TROMBOCYTES AT DENGUE HEMORRHAGIC FEVER (DHF) SCIENCE IN THE INSTALLATION OF DISEASE IN HOSPITAL DR. M. DJAMIL PADANG By SEPTI MUHARNI Advised by Prof. Dr. Almahdy A,MS, Apt; dr.Rose Dinda Martini,SpPD Dengue Hemorrhagic Fever (DHF)is contagious disease cawsed by dengue virus and transmitted from bite of aedes aegypti mosquito. Frequently prevention method given is ordering medicine and IVFD management. Non pharmacology method such as psidii folium extract and red fermented rice still not recomended. The purpose of this research is to know the effek use psidii folium extract management and red fermented rice at increase trombocytes in patient sufferings DHF at RSUP. DR. M. Djamil Padang. The research design quasi experimental with pre and post test design. The study was carried on from Februari to April 2011 in RSUP. DR. M. Djamil Padang and willing to give informed consent were included. The subject were 20 patient sufferi DHF in intenist word. Patients with hematology abnormality, heart and lung disease, salicylic acid treatment, severe hemorrhagic condition, and descent consciousness were excluded. Thrombocytes was done once every 12 hours every day. Furthermore, the changes of thrombocytes count from start to end were analyzed using t-independent-test (to analyze the difference of changes between groups) and chi- square (to analyze the response rate between groups). In this trial of 20 subjects, the thrombocytes count of the test group was significantly increased compared with the control group p≤0.05 (p=0,0120) and the increasing of thrombocytes response rate in the test group was significantly different from that in the control group p≤0.01 (p=0,0034). In conclusion, the results of this trial have proven that Psidii folium extract could treat thrombocytopenia.