Int.J.ofComputers,Communications&Control,ISSN1841-9836,E-ISSN1841-9844 Vol.III(2008),Suppl.issue:ProceedingsofICCCC2008,pp.491-496 Towards Great Challenge for Enterprise Science Within Knowledge-based Society Paradigm AurelianM.St˘ anescu,LucianM.Ionescu,AdinaFlorea, C.¸ Serb˘ anescu,MihneaA.Moisescu,IoanS.Sacala Abstract: The paper is aiming at launching the debate / forum to discuss the new scien- tificdisciplineof“e-Enterprise”(e-E)withintheknowledge-basedSocietyparadigm. There are great challenges to support the solid foundation of the new “science”, copying with the requirementslistofKnowledge-basedsocietyfocusingonglobalizationande-democracyap- proachfore-Enterprise.Thefirstkey-driveristhecoherentandconsistentnewmethodology forGeneralSystemTheorybasedmodeling,analysis,performanceevaluationandconceptual designofe-Enterprise.ThesecondoneconcernswithDigitalWorldTheoryandApplications basedonadvancedresearchinMathematics,PhysicsandComputingPractice. ARomanian NationalResearchfunding-basedproject“REMEDIUM”(environment4health)isusedasa complexstudycase. Keywords: complexadaptivesystems,metamodelingframework,digitalworldtheory. 1 Introduction ThetransitionfromthePostindustrialSociety(PS)towardsKnowledge-basedSociety(KbS)viaTheInforma- tionSociety(IS)generatesmanyparadigmshifts,aswellasgreatchallenges.Alldailyactivitieslikehealthcaresys- tems, administration / e-government, education / lifelong learning/e-learning, culture business(from e-Commerce toward Knowledge - based Business), way of working/e-work and last, but not least Interoperability - focused networkedEnterprisenetworking(virtual,extended,collaborative,a.s.o)arehighpriorityresearchagendaofthou- sandsofLabsworldwide. Oneoftheauthor’spresentpaper(AurelianM.Stanescu)hasjustcontributedatkey-issue,includedin“Vision and Roadmap of Enterprise Interoperability” namely the “Systems and Complexity Science”. Enterprises have manystructuresandrelationships. Understandingtheirinteractionsisconsideredamajorfactorincontributingto thesuccessofinteroperabilitysolutionsandtheperformanceofthenetworkenterprise[ExtendedEnterprise(EE), VirtualEnterprise(VE),CollaborativeNetworkOrganization(CNO)].ThesustainableenterprisesareCOMPLEX ADAPTIVE SYSTEMS (CAS) [I. Dumitrache, A.M.Stanescu 2007]. Moreover, with reference to the concerted researchroadmapforshapingbusinessintheKnowledge-basedEconomy,theyarealsocomponentswithinoneor moreinnovativeecosystem[A.M.Stanescu2007].Theevaluationofcomplexityinthese“SystemofSystems”with “star-topologyor”“pear-to-pear”ICTplatformtopologyareinprogresstobeconsolidated. Someresearchers have attempted to extrapolate the results to a “General System Theory (GST)”. This GTS could explain the be- havior modeling of the CAS. This theory views all systems as dynamic, living entities that are goal-oriented and that evolve over time [Molina,2007]. Complexity science, generally considered as a branch of systems science, has been developed to address the emergence, adaptation, evolution, and self - organization of such systems. In particular,itconcernsthecouplingandinteractionsofthepartswithinthesesystemsinanonlinearfashion. Mc Chutchy and F. Gensfeld, from Industrial System Division of M.I.T. has already highlighted the great challengefornotonlymodeling,butanalysis,performanceevaluationandsynthesisoftheCAS-conceptsbased socio - technological - economic systems, towards the contextual systems. In comparison with the “old” signal processing - based system (automatic control - oriented systems) the degree of complexity, as well as the degree ofuncertaintyareexponentiallyincreased. On the other hand, two new ideas has been created the context to develop our research topics. Prof. Shimon Nof, from the Purdue University/Prism Center provided two key - conferences [INCOM 06], [IFAC - MCPL]. ThesepapershavejustopenthewaytotheholisticapproachfortheCASinvolvingkeyfeaturesofinteroperability, scalability,selforganizing,andavailabilityvector. The paper is concerned with launching the debate for a promising new scientific discipline “e - Enterprise” - Science.Thestructureofmaterialisthefollowing: 1. GeneralSystemTheory-orientedFramework 2. Metamodeling-focusednewapproachforCASine-Enterprise Copyright©2006-2008byCCCPublications-AgoraUniversityEd.House.Allrightsreserved.