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Indo American Journal of Pharmaceutical Research, 2013 ISSN NO: 2231-6876
Journal home page:
http://www.iajpr.com/index.php/en/
INDO AMERICAN
JOURNAL OF
PHARMACEUTICAL
RESEARCH
Introduction To Diels Alder Reaction, Its Mechanism And Recent Advantages: A Review
Sarbjeet Singh Gujral
1
* and Anurag Popli
1
Maharaja Surajmal Institute of Pharmacy (Aff. To GGS Indraprastha University
Corresponding author
Sarbjeet Singh Gujral
Maharaja Surajmal Institute of Pharmacy (Aff. To GGS Indraprastha University),
C-4, Janakpuri,
New Delhi-110058, India
Contact No.: + 91-9871334787
E-mail ID: sarbjeet_singh18@yahoo.in
Copy right © 2013 This is an Open Access article distributed under the terms of the Indo American journal of Pharmaceutical
Research, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly
cited.
ARTICLE INFO ABSTRACT
Article history
Received 27/09/2013
Available online
28/04/2013
Keywords
Diels Alder Synthesis,
natural products, medicinal
Chemistry, complete
synthesis
The Diels-Alder reaction is one of the most versatile reactions known to the organic
chemists. This reaction was named after Scientists who discovered this reaction, Otto Diels
and Kurt Alder (Research Student of Otto Diels).This discovery led both of them the Nobel
Prize in Chemistry in the year 1950. This reaction has been successfully utilized in the
synthesis of many of the complex organic molecules like Reserpine, Cholesterol,
Gibberellic acid, Ambruticins, myrocin C, (-) colombiasin A, Antibiotic X-14547 A etc.
The present review article emphasis on introduction, mechanism, applications and some of
the recent advantages of this reaction. A special emphasis has been laid on the application
of this reaction in the synthesis of natural products and its complete synthesis and also to
other molecules with known pharmacological actions.
Please cite this article in press as Sarbjeet Singh Gujral et al. Introduction to Diels Alder Reaction Its Mechanism and Recent
Advantages: A Review. Indo American Journal of Pharm Research.2013:3(4).