Author's personal copy chemical engineering research and design 89 (2011) 347–351 Contents lists available at ScienceDirect Chemical Engineering Research and Design journal homepage: www.elsevier.com/locate/cherd Short communication Numerical analysis of residence time distribution in microchannels A. Vikhansky School of Engineering and Material Science, Queen Mary, University of London, United Kingdom abstract This article describes a numerical approach, which allows for the analysis of the residence time distribution (RTD) in microchannels. While the traditional methods provide the RTD at the outlet of the reactor, we consider the distribu- tion of the tracer’s age across the entire flowfield. The equation for the tracer’s age distribution is solved by a modified method of moments and the distribution function is calculated by a reconstruction procedure. As an example we consider a Dean vortex-based micromixer. © 2010 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved. Keywords: RTD; Dean flow; Microchannels 1. Introduction The residence time distribution (RTD) is one of the key char- acteristics that determines the performance of a chemical reactor (Danckwerts, 1953; Levenspiel, 1972; Cozewith and Squire, 2000). Although the concept of RTD has been well- established during the last 50 years and has been recently extended to unsteady-state flows (Rawatlal and Starzak, 2003), RTDs remain a focus of interest in the chemical engineer- ing community. Recent progress in microfluidic technology has turned researchs’ attention to the RTDs in microcdevices, usually operated under laminar regimes (Vikhansky, 2008a; Adeosun and Lawal, 2009; Cantu-Perez et al., 2010; Vikhansky and MacInnes, in press) The problem is formulated as following. Consider the flow of a viscous incompressible liquid through a microchannel, e.g., similar to that shown in Fig. 1. The flowfield is described by the Navier–Stokes equations, namely · u = 0,( t + u · ) u =− p +  2 u, (1) where u, p, and are velocity, pressure, density and the kinematic viscosity. Due to the non-uniform velocity, different particles spend different time in the channel and the par- E-mail address: a.vikhansky@qmul.ac.uk. Received 30 November 2009; Received in revised form 13 May 2010; Accepted 18 June 2010 ticles leaving the channel at time t have been injected into the channel at different times in the past. The flux-averaged concentration of an admixture at the outlet C out (t) is related through the RTD to the flux-averaged concentration at the entrance C in (t ) (where t t) as C out (t) = 0 E(t,  )C in (t )d. (2) This formula constitutes the mathematical definition of E(·,·)(Levenspiel, 1972). The spread in the residence times implies that different portions of the fluid have different chemical composition. Knowledge of the RTD allows for exact calculation of the yield of a first-order reaction and provides a crude estimate for the yield of higher-order reactions. Surprisingly, in spite of the widely recognized importance of the RTD, very little has been done to develop the corresponding numerical algorithms. The most commonly used numerical methods to calculate the RTD is based on particle tracking (Cantu-Perez et al., 2010), which works as follows. Consider a massless particle advected by the flowfield: when a particle enters the channel its age s is 0 and then it increases with time according to the differential equa- tion ds/dt = 1. The position and age of a particle is governed 0263-8762/$ – see front matter © 2010 The Institution of Chemical Engineers. Published by Elsevier B.V. All rights reserved. doi:10.1016/j.cherd.2010.06.010